Efficacy of istradefylline for gait disorders with freezing of gait in Parkinson’s disease: A single-arm, open-label, prospective, multicenter study

Background: Gait disorders are common in Parkinson’s disease patients who respond poorly to dopaminergic treatment. Blockade of adenosine A2A receptors is expected to improve gait disorders. Istradefylline is a first-in-class selective adenosine A2A receptor antagonist with benefits for motor compli...

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Hauptverfasser: Iijima, Mutsumi, Orimo, Satoshi, Terashi, Hiroo, Suzuki, Masahiko, Hayashi, Akito, Shimura, Hideki, Mitoma, Hiroshi, Kitagawa, Kazuo, Okuma, Yasuyuki
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Sprache:eng
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