Reversal of uremic tumoral calcinosis by optimization of clinical treatment of bone and mineral metabolism disorder
Abstract Tumoral calcinosis is an uncommon type of extraosseous calcification characterized by large rubbery or cystic masses containing calcium-phosphate deposits. The condition prevails in the periarticular tissue with preservation of osteoarticular structures. Elevated calcium-phosphorus products...
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creator | Maioli, Mariana Espiga Delfino, Vinicius Daher Alvares Guerra, Amanda Carolina Damasceno Zanuto Luiz Fernando Kunii Frange, Raquel Ferreira Nassar |
description | Abstract Tumoral calcinosis is an uncommon type of extraosseous calcification characterized by large rubbery or cystic masses containing calcium-phosphate deposits. The condition prevails in the periarticular tissue with preservation of osteoarticular structures. Elevated calcium-phosphorus products and severe secondary hyperparathyroidism are present in most patients with uremic tumoral calcionosis (UTC). Case report of an obese secondary to chronic glomerulonephritis, undergoing continuous ambulatory peritoneal dialysis (CAPD) reported the appearance of painless tumors in the medial surface of fifth finger and left arm. Tumoral calcinosis was confirmed by left biceps biopsy. Poor adherence to CAPD. The patient was transferred to the "tidal" modality of peritoneal dialysis and after was treated by hemodialysis, despite the persistence of severe hyperparathyroidism progressive reduction of UTC until near to its complete disappearance. Nowadays, one year after patient received deceased-donor kidney transplantation, he presents with an improvement in secondary hyperparathyroidism. UTC should be included in the elucidation of periarticular calcification of every patient on dialysis. Relevant laboratory findings such as secondary hyperparathyroidism and elevated calcium- phosphorus products in the presence of periarticular calcification should draw attention to the diagnosis of UTC. |
doi_str_mv | 10.6084/m9.figshare.5670481 |
format | Dataset |
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The condition prevails in the periarticular tissue with preservation of osteoarticular structures. Elevated calcium-phosphorus products and severe secondary hyperparathyroidism are present in most patients with uremic tumoral calcionosis (UTC). Case report of an obese secondary to chronic glomerulonephritis, undergoing continuous ambulatory peritoneal dialysis (CAPD) reported the appearance of painless tumors in the medial surface of fifth finger and left arm. Tumoral calcinosis was confirmed by left biceps biopsy. Poor adherence to CAPD. The patient was transferred to the "tidal" modality of peritoneal dialysis and after was treated by hemodialysis, despite the persistence of severe hyperparathyroidism progressive reduction of UTC until near to its complete disappearance. Nowadays, one year after patient received deceased-donor kidney transplantation, he presents with an improvement in secondary hyperparathyroidism. UTC should be included in the elucidation of periarticular calcification of every patient on dialysis. Relevant laboratory findings such as secondary hyperparathyroidism and elevated calcium- phosphorus products in the presence of periarticular calcification should draw attention to the diagnosis of UTC.</description><identifier>DOI: 10.6084/m9.figshare.5670481</identifier><language>eng</language><publisher>SciELO journals</publisher><subject>FOS: Clinical medicine ; Nephrology and Urology</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776,1888</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.6084/m9.figshare.5670481$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Maioli, Mariana Espiga</creatorcontrib><creatorcontrib>Delfino, Vinicius Daher Alvares</creatorcontrib><creatorcontrib>Guerra, Amanda Carolina Damasceno Zanuto</creatorcontrib><creatorcontrib>Luiz Fernando Kunii</creatorcontrib><creatorcontrib>Frange, Raquel Ferreira Nassar</creatorcontrib><title>Reversal of uremic tumoral calcinosis by optimization of clinical treatment of bone and mineral metabolism disorder</title><description>Abstract Tumoral calcinosis is an uncommon type of extraosseous calcification characterized by large rubbery or cystic masses containing calcium-phosphate deposits. The condition prevails in the periarticular tissue with preservation of osteoarticular structures. Elevated calcium-phosphorus products and severe secondary hyperparathyroidism are present in most patients with uremic tumoral calcionosis (UTC). Case report of an obese secondary to chronic glomerulonephritis, undergoing continuous ambulatory peritoneal dialysis (CAPD) reported the appearance of painless tumors in the medial surface of fifth finger and left arm. Tumoral calcinosis was confirmed by left biceps biopsy. Poor adherence to CAPD. The patient was transferred to the "tidal" modality of peritoneal dialysis and after was treated by hemodialysis, despite the persistence of severe hyperparathyroidism progressive reduction of UTC until near to its complete disappearance. Nowadays, one year after patient received deceased-donor kidney transplantation, he presents with an improvement in secondary hyperparathyroidism. UTC should be included in the elucidation of periarticular calcification of every patient on dialysis. Relevant laboratory findings such as secondary hyperparathyroidism and elevated calcium- phosphorus products in the presence of periarticular calcification should draw attention to the diagnosis of UTC.</description><subject>FOS: Clinical medicine</subject><subject>Nephrology and Urology</subject><fulltext>true</fulltext><rsrctype>dataset</rsrctype><creationdate>2017</creationdate><recordtype>dataset</recordtype><sourceid>PQ8</sourceid><recordid>eNo1kMtqwzAQRbXpoqT9gm70A3YlP2RrWUJfECiU7M1YGqUDlhQkpZB-fWOari5cDmdxGHuQolZi7B69rh0d8hckrHs1iG6Utyx_4jemDAuPjp8SejK8nHxMl8fAYijETJnPZx6PhTz9QKEYVtgsFOiC8JIQisdQ1neOATkEyz0FXCUeC8xxoey5pRyTxXTHbhwsGe-vu2H7l-f99q3afby-b592lR21rHp0Enph5TBiOyoptBVadsoN2inVSTXL1naN6ITppWpsP4AamsbAhTJCuXbD2j-thQKGCk7HRB7SeZJiWotMXk__RaZrkfYXHe1ekA</recordid><startdate>20171205</startdate><enddate>20171205</enddate><creator>Maioli, Mariana Espiga</creator><creator>Delfino, Vinicius Daher Alvares</creator><creator>Guerra, Amanda Carolina Damasceno Zanuto</creator><creator>Luiz Fernando Kunii</creator><creator>Frange, Raquel Ferreira Nassar</creator><general>SciELO journals</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20171205</creationdate><title>Reversal of uremic tumoral calcinosis by optimization of clinical treatment of bone and mineral metabolism disorder</title><author>Maioli, Mariana Espiga ; Delfino, Vinicius Daher Alvares ; Guerra, Amanda Carolina Damasceno Zanuto ; Luiz Fernando Kunii ; Frange, Raquel Ferreira Nassar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-d891-5ef1a50d178e386109d09146f79f66416b13d42040c5162d57a6722ca091c06f3</frbrgroupid><rsrctype>datasets</rsrctype><prefilter>datasets</prefilter><language>eng</language><creationdate>2017</creationdate><topic>FOS: Clinical medicine</topic><topic>Nephrology and Urology</topic><toplevel>online_resources</toplevel><creatorcontrib>Maioli, Mariana Espiga</creatorcontrib><creatorcontrib>Delfino, Vinicius Daher Alvares</creatorcontrib><creatorcontrib>Guerra, Amanda Carolina Damasceno Zanuto</creatorcontrib><creatorcontrib>Luiz Fernando Kunii</creatorcontrib><creatorcontrib>Frange, Raquel Ferreira Nassar</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Maioli, Mariana Espiga</au><au>Delfino, Vinicius Daher Alvares</au><au>Guerra, Amanda Carolina Damasceno Zanuto</au><au>Luiz Fernando Kunii</au><au>Frange, Raquel Ferreira Nassar</au><format>book</format><genre>unknown</genre><ristype>DATA</ristype><title>Reversal of uremic tumoral calcinosis by optimization of clinical treatment of bone and mineral metabolism disorder</title><date>2017-12-05</date><risdate>2017</risdate><abstract>Abstract Tumoral calcinosis is an uncommon type of extraosseous calcification characterized by large rubbery or cystic masses containing calcium-phosphate deposits. The condition prevails in the periarticular tissue with preservation of osteoarticular structures. Elevated calcium-phosphorus products and severe secondary hyperparathyroidism are present in most patients with uremic tumoral calcionosis (UTC). Case report of an obese secondary to chronic glomerulonephritis, undergoing continuous ambulatory peritoneal dialysis (CAPD) reported the appearance of painless tumors in the medial surface of fifth finger and left arm. Tumoral calcinosis was confirmed by left biceps biopsy. Poor adherence to CAPD. The patient was transferred to the "tidal" modality of peritoneal dialysis and after was treated by hemodialysis, despite the persistence of severe hyperparathyroidism progressive reduction of UTC until near to its complete disappearance. Nowadays, one year after patient received deceased-donor kidney transplantation, he presents with an improvement in secondary hyperparathyroidism. UTC should be included in the elucidation of periarticular calcification of every patient on dialysis. Relevant laboratory findings such as secondary hyperparathyroidism and elevated calcium- phosphorus products in the presence of periarticular calcification should draw attention to the diagnosis of UTC.</abstract><pub>SciELO journals</pub><doi>10.6084/m9.figshare.5670481</doi><oa>free_for_read</oa></addata></record> |
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subjects | FOS: Clinical medicine Nephrology and Urology |
title | Reversal of uremic tumoral calcinosis by optimization of clinical treatment of bone and mineral metabolism disorder |
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