Regulation of RNA polymerase III transcription during transformation of human IMR90 fibroblasts with defined genetic elements

RNA polymerase (Pol) III transcribes small untranslated RNAs that are essential for cellular homeostasis and growth. Its activity is regulated by inactivation of tumor suppressor proteins and overexpression of the oncogene c-MYC, but the concerted action of these tumor-promoting factors on Pol III t...

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Hauptverfasser: Durrieu-Gaillard, Stéphanie, Dumay-Odelot, Hélène, Boldina, Galina, Tourasse, Nicolas J., Allard, Delphine, André, Fabrice, Macari, Françoise, Choquet, Armelle, Lagarde, Pauline, Drutel, Guillaume, Leste-Lasserre, Thierry, Petitet, Marion, Lesluyes, Tom, Lartigue-Faustin, Lydia, Jean-William Dupuy, Chibon, Frédéric, Roeder, Robert G., Joubert, Dominique, Vagner, Stéphan, Teichmann, Martin
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Sprache:eng
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