HSP70 suppresses TNF-α induced phosphorylation of MAPKs in human FLSs
Rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) were incubated with heat shock protein (HSP)70 at 0.1 to 10 μg/ml for 1 hour, and the FLSs were washed and exposed to tumour necrosis factor (TNF)-α (20 ng/ml) for 30 minutes. The cell lysates were immunoblotted with anti-phospho-p38 (p-p...
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