Additional file 8 of UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer

Additional file 8: Supplementary Figure 3. Total collagen content of fibroblasts was measured after 3 days culture in conditioned medium from: A) HEYA8 control cells (shneg) or HEYA8 cells with UGDH knocked down (sh459. sh939) compared to culture medium (M), B) SKOV3 cells with UGDH overexpression (...

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Hauptverfasser: Harrington, Brittney S., Kamdar, Rahul, Ning, Franklin, Korrapati, Soumya, Caminear, Michael W., Hernandez, Lidia F., Butcher, Donna, Edmondson, Elijah F., Traficante, Nadia, Hendley, Joy, Gough, Madeline, Rogers, Rebecca, Lourie, Rohan, Shetty, Jyoti, Tran, Bao, Elloumi, Fathi, Abdelmaksoud, Abdalla, Nag, Madhu Lal, Mazan-Mamczarz, Krystyna, House, Carrie D., Hooper, John D., Annunziata, Christina M.
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Sprache:eng
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Zusammenfassung:Additional file 8: Supplementary Figure 3. Total collagen content of fibroblasts was measured after 3 days culture in conditioned medium from: A) HEYA8 control cells (shneg) or HEYA8 cells with UGDH knocked down (sh459. sh939) compared to culture medium (M), B) SKOV3 cells with UGDH overexpression (OverX) or vector control (VC) compared to culture medium (M). C) Expression of IL-6 and D) IL-8 in supernatant from HEYA8 adherent cells or spheroids with UGDH knockdown (sh459, sh939) compared to controls (shneg). E) Expression of IL-6 and F) IL-8 in supernatant from SKOV3 cells with UGDH overexpression (OverX) or vector control (VC). *p
DOI:10.6084/m9.figshare.26628916