The Role of Neuro-Immune Interactions in the Pathology and Pathogenesis of Allergic Rhinitis

Allergic rhinitis (AR) is a non-infectious inflammatory disease of the nasal mucosa mediated by IgE and involving a variety of immune cells such as mast cells. In previous studies, AR was considered as an isolated disease of the immune system. However, recent studies have found that the nervous syst...

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Hauptverfasser: Lan, Ya-An, Guo, Jia-Xi, Yao, Min-Hua, Kang, Yi-Ting, Liao, Zi-Rui, Jing, Yu-Hong
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Guo, Jia-Xi
Yao, Min-Hua
Kang, Yi-Ting
Liao, Zi-Rui
Jing, Yu-Hong
description Allergic rhinitis (AR) is a non-infectious inflammatory disease of the nasal mucosa mediated by IgE and involving a variety of immune cells such as mast cells. In previous studies, AR was considered as an isolated disease of the immune system. However, recent studies have found that the nervous system is closely related to the development of AR. Bidirectional communication between the nervous and immune systems plays an important role in AR. The nervous system and immune system depend on the anatomical relationship between nerve fibers and immune cells, as well as various neurotransmitters, cytokines, inflammatory mediators, etc. to produce bidirectional connections, which affect the development of AR. This article reviews the impact of neuro-immune interactions in AR on the development of AR, including neuro-immune cell units.
doi_str_mv 10.6084/m9.figshare.26357030
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identifier DOI: 10.6084/m9.figshare.26357030
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subjects Biological Sciences not elsewhere classified
Developmental Biology
FOS: Biological sciences
FOS: Clinical medicine
Genetics
Immunology
Medicine
Mental Health
title The Role of Neuro-Immune Interactions in the Pathology and Pathogenesis of Allergic Rhinitis
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