Supplementary Material for: Intensive blood pressure lowering and renal function in ischemic stroke patients: secondary analysis of ENCHANTED trial

Background: Renal failure is a major safety concern of intensive systolic blood pressure (SBP) lowering. We aimed to determine the effect of this treatment on early change in renal function in participants of the international Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED...

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Hauptverfasser: C., Chen, X., Ren, Y., Zhao, M., Ouyang, Q., LiMbiostat, X., Wang, Y., Li, S., You, Y., Wang, T.G., Robinson, R.I., Lindley, H., Arima, J., Chalmers, G., Li, X., Chen, C.S., Anderson, L., Song
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Sprache:eng
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Zusammenfassung:Background: Renal failure is a major safety concern of intensive systolic blood pressure (SBP) lowering. We aimed to determine the effect of this treatment on early change in renal function in participants of the international Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED). Methods: Post-hoc analysis of the ENCHANTED BP-arm in which thrombolyzed patients with acute ischemic stroke (AIS) were randomized to intensive (target 130-140 mm Hg within 1 h) or guideline-recommended (target
DOI:10.6084/m9.figshare.25001819