In vivo delivery of engineered synthetic DNA-encoded SARS-CoV-2 monoclonal antibodies for pre-exposure prophylaxis in non-human primates

COVID-19 remains a major public health concern. Monoclonal antibodies have received emergency use authorization (EUA) for pre-exposure prophylaxis against COVID-19 among high-risk groups for treatment of mild to moderate COVID-19. In addition to recombinant biologics, engineered synthetic DNA-encode...

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Hauptverfasser:	Patel, Ami, Rosenke, Kyle, Parzych, Elizabeth M., Feldmann, Friederike, Bharti, Suman, Griffin, Amanda J., Schouest, Blake, Lewis, Matt, Choi, Jihae, Chokkalingam, Neethu, Machado, Viviane, Smith, Brian J., Frase, Drew, Ali, Ali R., Lovaglio, Jamie, Nguyen, Brian, Hanley, Patrick W., Walker, Susanne N., Gary, Ebony N., Kulkarni, Abhijeet, Generotti, Allison, Francica, Joseph R., Rosenthal, Kim, Kulp, Daniel W., Esser, Mark T., Smith, Trevor R. F., Shaia, Carl, Weiner, David B., Feldmann, Heinz
Format:	Dataset
Sprache:	eng
Schlagworte:	Biochemistry Cancer FOS: Clinical medicine FOS: Health sciences Immunology Infectious Diseases Medicine Molecular Biology Pharmacology Space Science
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