Additional file 10 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Additional file 10: (A) BLCA with lymphovascular invasion expressed more FAP and VCAN than without lymphovascular invasion. In OS (B) and DSS (C) events, FAP, VCAN, N-cadherin, and Vimentin expression in the deceased group is higher than in the alive group. (D) In PFI events, VCAN and N-cadherin are...
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| creator | Ping, Qinrong Wang, Chunhui Cheng, Xin Zhong, Yiming Yan, Ruping Yang, Meng Shi, Yunqiang Li, Xiangmeng Li, Xiao Huang, Wenwen Wang, Liqiong Bi, Xiaofang Hu, Libing Yang, Yang Wang, Yingbao Gong, Rui Tan, Jun Li, Rui Li, Hui Li, Jian Wang, Wenju Li, Ruhong |
| description | Additional file 10: (A) BLCA with lymphovascular invasion expressed more FAP and VCAN than without lymphovascular invasion. In OS (B) and DSS (C) events, FAP, VCAN, N-cadherin, and Vimentin expression in the deceased group is higher than in the alive group. (D) In PFI events, VCAN and N-cadherin are more highly expressed in the deceased group. Immunohistochemistry (E) and dot blot (F) shows that the expression of TGF-β1, FAP, VCAN, N-cadherin, and Vimentin in BLCA tissues is significantly higher than in adjacent normal tissues, while the expression of E-cadherin in BLCA tissues is lower than in adjacent normal tissues. (G) TGF-β1 dominates stromal fibroblast-mediated EMT of bladder cancer cells via the FAP/VCAN axis to promote the invasion and metastasis of BLCA. |
| doi_str_mv | 10.6084/m9.figshare.23700675 |
| format | Dataset |
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In OS (B) and DSS (C) events, FAP, VCAN, N-cadherin, and Vimentin expression in the deceased group is higher than in the alive group. (D) In PFI events, VCAN and N-cadherin are more highly expressed in the deceased group. Immunohistochemistry (E) and dot blot (F) shows that the expression of TGF-β1, FAP, VCAN, N-cadherin, and Vimentin in BLCA tissues is significantly higher than in adjacent normal tissues, while the expression of E-cadherin in BLCA tissues is lower than in adjacent normal tissues. (G) TGF-β1 dominates stromal fibroblast-mediated EMT of bladder cancer cells via the FAP/VCAN axis to promote the invasion and metastasis of BLCA.</description><identifier>DOI: 10.6084/m9.figshare.23700675</identifier><language>eng</language><publisher>figshare</publisher><subject>Cancer ; Cell Biology ; FOS: Biological sciences ; FOS: Clinical medicine ; Genetics ; Immunology ; Medicine ; Molecular Biology ; Physiology</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0003-2435-7760</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>781,1895</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.6084/m9.figshare.23700675$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ping, Qinrong</creatorcontrib><creatorcontrib>Wang, Chunhui</creatorcontrib><creatorcontrib>Cheng, Xin</creatorcontrib><creatorcontrib>Zhong, Yiming</creatorcontrib><creatorcontrib>Yan, Ruping</creatorcontrib><creatorcontrib>Yang, Meng</creatorcontrib><creatorcontrib>Shi, Yunqiang</creatorcontrib><creatorcontrib>Li, Xiangmeng</creatorcontrib><creatorcontrib>Li, Xiao</creatorcontrib><creatorcontrib>Huang, Wenwen</creatorcontrib><creatorcontrib>Wang, Liqiong</creatorcontrib><creatorcontrib>Bi, Xiaofang</creatorcontrib><creatorcontrib>Hu, Libing</creatorcontrib><creatorcontrib>Yang, Yang</creatorcontrib><creatorcontrib>Wang, Yingbao</creatorcontrib><creatorcontrib>Gong, Rui</creatorcontrib><creatorcontrib>Tan, Jun</creatorcontrib><creatorcontrib>Li, Rui</creatorcontrib><creatorcontrib>Li, Hui</creatorcontrib><creatorcontrib>Li, Jian</creatorcontrib><creatorcontrib>Wang, Wenju</creatorcontrib><creatorcontrib>Li, Ruhong</creatorcontrib><title>Additional file 10 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells</title><description>Additional file 10: (A) BLCA with lymphovascular invasion expressed more FAP and VCAN than without lymphovascular invasion. In OS (B) and DSS (C) events, FAP, VCAN, N-cadherin, and Vimentin expression in the deceased group is higher than in the alive group. (D) In PFI events, VCAN and N-cadherin are more highly expressed in the deceased group. Immunohistochemistry (E) and dot blot (F) shows that the expression of TGF-β1, FAP, VCAN, N-cadherin, and Vimentin in BLCA tissues is significantly higher than in adjacent normal tissues, while the expression of E-cadherin in BLCA tissues is lower than in adjacent normal tissues. 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| subjects | Cancer Cell Biology FOS: Biological sciences FOS: Clinical medicine Genetics Immunology Medicine Molecular Biology Physiology |
| title | Additional file 10 of TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells |
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