Suppl. Figure 1. Activity during tickling compared to the touch and the touch with voluntary vocalization conditions from When laughter arrests speech: fMRI-based evidence

Panel a: Brain activation during tickling compared to monotonous foot contacts (touch). Activation of the anterior (AI), posterior (PI) and limen (LI) parts of the insular cortex, of the primary sensorimotor cortex (S1/M1), the anterior cingulate cortex (ACC), the subcallosal area (SCA), the hypothalamus (HYP), the periaqueductal gray (PAG), and the brainstem lateral tegmental field in the area of the nucleus ambiguus (AMB) is indicated. In the illustrated example, the level of significance for threshold activity was set at p < 0.05 (FWE corrected). Panel b: Brain activation during tickling compared to monotonous foot contacts (touch) with voluntary vocalisation. Activation of the anterior (AI), posterior (PI) and limen (LI) parts of the insular cortex, of the primary sensorimotor cortex (S1/M1), the anterior cingulate cortex (ACC), the hypothalamus (Hyp), and the periaqueductal gray (PAG) is indicated. In the illustrated example, the level of significance for threshold activity was set at p < 0.05 (FWE corrected).