Multivariate Optimization Applied to the Synthesis of Meglumine Antimoniate with Low Levels of Trivalent Antimony

Meglumine antimoniate (MA) is a pentavalent antimony (SbV) drug recommended for the treatment of leishmaniasis. It is known that the trivalent antimony (SbIII) present as a residue in MA contributes to the drug side effects. In this article, multivariate optimization was used in the synthesis of MA...

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Hauptverfasser: Fabrino, Henrique J. F., Frezard, Frédéric J. G., Oliveira, Ana Carolina B. de, Costa, Letícia M., Demicheli, Cynthia P.
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Sprache:eng
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