Additional file 4 of Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress
Additional file 4: Figure S2. Endurance exercise does not increase irradiated muscle mass. EDL (left) and soleus (right). Raw muscle mass (mg) of a) EDL and b) soleus muscle from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedent...
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| creator | O’Connor, Thomas N. Kallenbach, Jacob G. Orciuoli, Haley M. Paris, Nicole D. Bachman, John F. Johnston, Carl J. Hernady, Eric Williams, Jacqueline P. Dirksen, Robert T. Chakkalakal, Joe V. |
| description | Additional file 4: Figure S2. Endurance exercise does not increase irradiated muscle mass. EDL (left) and soleus (right). Raw muscle mass (mg) of a) EDL and b) soleus muscle from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. c, d) Lean muscle mass (muscle mass/body mass), from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. e) Myofiber cross-sectional area (CSA) from EDL and f) soleus muscle. Biological n=3 mice per condition, technical n value displayed directly on graph as number of myofibers measured per condition. Two-way ANOVA with multiple comparisons, * p |
| doi_str_mv | 10.6084/m9.figshare.19588989 |
| format | Video |
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Endurance exercise does not increase irradiated muscle mass. EDL (left) and soleus (right). Raw muscle mass (mg) of a) EDL and b) soleus muscle from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. c, d) Lean muscle mass (muscle mass/body mass), from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. e) Myofiber cross-sectional area (CSA) from EDL and f) soleus muscle. Biological n=3 mice per condition, technical n value displayed directly on graph as number of myofibers measured per condition. Two-way ANOVA with multiple comparisons, * p<0.05, **/## p<0.01, ***/### p<0.001, ***/### p<0.0001. Isolated asterisks denote ANOVA group effect of exercise. Isolated pound signs denote ANOVA group effect of radiation. Significant interaction between variables was observed in analysis of EDL CSA in e), p=0.033. 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Endurance exercise does not increase irradiated muscle mass. EDL (left) and soleus (right). Raw muscle mass (mg) of a) EDL and b) soleus muscle from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. c, d) Lean muscle mass (muscle mass/body mass), from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. e) Myofiber cross-sectional area (CSA) from EDL and f) soleus muscle. Biological n=3 mice per condition, technical n value displayed directly on graph as number of myofibers measured per condition. Two-way ANOVA with multiple comparisons, * p<0.05, **/## p<0.01, ***/### p<0.001, ***/### p<0.0001. Isolated asterisks denote ANOVA group effect of exercise. Isolated pound signs denote ANOVA group effect of radiation. Significant interaction between variables was observed in analysis of EDL CSA in e), p=0.033. Data displayed as mean +/- s.e.m.</description><subject>Astronomical and Space Sciences not elsewhere classified</subject><subject>Biophysics</subject><subject>Cancer</subject><subject>Cell Biology</subject><subject>Environmental Sciences not elsewhere classified</subject><subject>FOS: Biological sciences</subject><subject>FOS: Earth and related environmental sciences</subject><subject>FOS: Physical sciences</subject><subject>Medicine</subject><subject>Molecular Biology</subject><subject>Neuroscience</subject><subject>Physical Sciences not elsewhere classified</subject><subject>Physiology</subject><fulltext>true</fulltext><rsrctype>video</rsrctype><creationdate>2022</creationdate><recordtype>video</recordtype><sourceid>PQ8</sourceid><recordid>eNqdjzFOBDEMRdNQIOAGFLnADjNiQJMSoUUcgD6yEmfXkGSQ7SA4A5cmI-1egMqF_3vSM-Z2GofHcZnvihsSHeQIjMPkHpbFLe7S_D7FSEprhWwTZbSzXZPd19gYakCL38iBBC2oYm2gKPa9fWHdtsQMkWDDd9SRgNHKB2bUbitNQt-kVsPJHzFkql1Voy2kaziuNTL1jyijyLW5SJAFb073yswv-7fn110EhUCK_pOpAP_4afRbky_On5v8uen-n9gf0lRkFw</recordid><startdate>20220413</startdate><enddate>20220413</enddate><creator>O’Connor, Thomas N.</creator><creator>Kallenbach, Jacob G.</creator><creator>Orciuoli, Haley M.</creator><creator>Paris, Nicole D.</creator><creator>Bachman, John F.</creator><creator>Johnston, Carl J.</creator><creator>Hernady, Eric</creator><creator>Williams, Jacqueline P.</creator><creator>Dirksen, Robert T.</creator><creator>Chakkalakal, Joe V.</creator><general>figshare</general><scope>DYCCY</scope><scope>PQ8</scope><orcidid>https://orcid.org/0000-0002-8440-7312</orcidid></search><sort><creationdate>20220413</creationdate><title>Additional file 4 of Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress</title><author>O’Connor, Thomas N. ; Kallenbach, Jacob G. ; Orciuoli, Haley M. ; Paris, Nicole D. ; Bachman, John F. ; Johnston, Carl J. ; Hernady, Eric ; Williams, Jacqueline P. ; Dirksen, Robert T. ; Chakkalakal, Joe V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_6084_m9_figshare_195889893</frbrgroupid><rsrctype>videos</rsrctype><prefilter>videos</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Astronomical and Space Sciences not elsewhere classified</topic><topic>Biophysics</topic><topic>Cancer</topic><topic>Cell Biology</topic><topic>Environmental Sciences not elsewhere classified</topic><topic>FOS: Biological sciences</topic><topic>FOS: Earth and related environmental sciences</topic><topic>FOS: Physical sciences</topic><topic>Medicine</topic><topic>Molecular Biology</topic><topic>Neuroscience</topic><topic>Physical Sciences not elsewhere classified</topic><topic>Physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>O’Connor, Thomas N.</creatorcontrib><creatorcontrib>Kallenbach, Jacob G.</creatorcontrib><creatorcontrib>Orciuoli, Haley M.</creatorcontrib><creatorcontrib>Paris, Nicole D.</creatorcontrib><creatorcontrib>Bachman, John F.</creatorcontrib><creatorcontrib>Johnston, Carl J.</creatorcontrib><creatorcontrib>Hernady, Eric</creatorcontrib><creatorcontrib>Williams, Jacqueline P.</creatorcontrib><creatorcontrib>Dirksen, Robert T.</creatorcontrib><creatorcontrib>Chakkalakal, Joe V.</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>O’Connor, Thomas N.</au><au>Kallenbach, Jacob G.</au><au>Orciuoli, Haley M.</au><au>Paris, Nicole D.</au><au>Bachman, John F.</au><au>Johnston, Carl J.</au><au>Hernady, Eric</au><au>Williams, Jacqueline P.</au><au>Dirksen, Robert T.</au><au>Chakkalakal, Joe V.</au><genre>unknown</genre><ristype>VIDEO</ristype><title>Additional file 4 of Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress</title><date>2022-04-13</date><risdate>2022</risdate><abstract>Additional file 4: Figure S2. Endurance exercise does not increase irradiated muscle mass. EDL (left) and soleus (right). Raw muscle mass (mg) of a) EDL and b) soleus muscle from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. c, d) Lean muscle mass (muscle mass/body mass), from irradiated mouse contralateral (Rad CL) and irradiated (Rad RL) limbs, both exercised (running) and non-exercised (sedentary). n = 11 mice per condition. e) Myofiber cross-sectional area (CSA) from EDL and f) soleus muscle. Biological n=3 mice per condition, technical n value displayed directly on graph as number of myofibers measured per condition. Two-way ANOVA with multiple comparisons, * p<0.05, **/## p<0.01, ***/### p<0.001, ***/### p<0.0001. Isolated asterisks denote ANOVA group effect of exercise. Isolated pound signs denote ANOVA group effect of radiation. Significant interaction between variables was observed in analysis of EDL CSA in e), p=0.033. Data displayed as mean +/- s.e.m.</abstract><pub>figshare</pub><doi>10.6084/m9.figshare.19588989</doi><orcidid>https://orcid.org/0000-0002-8440-7312</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Astronomical and Space Sciences not elsewhere classified Biophysics Cancer Cell Biology Environmental Sciences not elsewhere classified FOS: Biological sciences FOS: Earth and related environmental sciences FOS: Physical sciences Medicine Molecular Biology Neuroscience Physical Sciences not elsewhere classified Physiology |
| title | Additional file 4 of Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress |
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