Additional file 3 of Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress
Additional file 3: Figure S1. Exercise post-juvenile irradiation improves disrupted muscle contractile kinetics. EDL (left) and soleus (right) ex vivo physiology contractile kinetics. a, g) Absolute force frequency curve for 500 ms electrical stimulation. b, h) Specific force frequency curve for 500...
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| creator | O’Connor, Thomas N. Kallenbach, Jacob G. Orciuoli, Haley M. Paris, Nicole D. Bachman, John F. Johnston, Carl J. Hernady, Eric Williams, Jacqueline P. Dirksen, Robert T. Chakkalakal, Joe V. |
| description | Additional file 3: Figure S1. Exercise post-juvenile irradiation improves disrupted muscle contractile kinetics. EDL (left) and soleus (right) ex vivo physiology contractile kinetics. a, g) Absolute force frequency curve for 500 ms electrical stimulation. b, h) Specific force frequency curve for 500 ms electrical stimulation, normalized to physiologic cross-sectional area (P-CSA). c, i) Impulse (mN*sec) measurements taken as area under the curve for 500ms stimulation at 150Hz. d, j) Specific impulse (mN*sec/mm2) normalized to P-CSa. e, k) Rate of activation (mN/sec) measurements of excited muscle time-to-peak muscle contraction. f, l) Rate of relaxation (mN/sec) measurements of time to baseline following excitation stimulus cessation. n = 3-6 mice per condition. Two-way ANOVA with multiple comparisons, */# p |
| doi_str_mv | 10.6084/m9.figshare.19588983 |
| format | Video |
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Exercise post-juvenile irradiation improves disrupted muscle contractile kinetics. EDL (left) and soleus (right) ex vivo physiology contractile kinetics. a, g) Absolute force frequency curve for 500 ms electrical stimulation. b, h) Specific force frequency curve for 500 ms electrical stimulation, normalized to physiologic cross-sectional area (P-CSA). c, i) Impulse (mN*sec) measurements taken as area under the curve for 500ms stimulation at 150Hz. d, j) Specific impulse (mN*sec/mm2) normalized to P-CSa. e, k) Rate of activation (mN/sec) measurements of excited muscle time-to-peak muscle contraction. f, l) Rate of relaxation (mN/sec) measurements of time to baseline following excitation stimulus cessation. n = 3-6 mice per condition. Two-way ANOVA with multiple comparisons, */# p<0.05, **/## p<0.01, ***/### p<0.001, ***/### p<0.0001. Isolated asterisks denote ANOVA group effect of exercise. Isolated pound signs denote ANOVA group effect of radiation. 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Exercise post-juvenile irradiation improves disrupted muscle contractile kinetics. EDL (left) and soleus (right) ex vivo physiology contractile kinetics. a, g) Absolute force frequency curve for 500 ms electrical stimulation. b, h) Specific force frequency curve for 500 ms electrical stimulation, normalized to physiologic cross-sectional area (P-CSA). c, i) Impulse (mN*sec) measurements taken as area under the curve for 500ms stimulation at 150Hz. d, j) Specific impulse (mN*sec/mm2) normalized to P-CSa. e, k) Rate of activation (mN/sec) measurements of excited muscle time-to-peak muscle contraction. f, l) Rate of relaxation (mN/sec) measurements of time to baseline following excitation stimulus cessation. n = 3-6 mice per condition. Two-way ANOVA with multiple comparisons, */# p<0.05, **/## p<0.01, ***/### p<0.001, ***/### p<0.0001. Isolated asterisks denote ANOVA group effect of exercise. Isolated pound signs denote ANOVA group effect of radiation. 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| subjects | Astronomical and Space Sciences not elsewhere classified Biophysics Cancer Cell Biology Environmental Sciences not elsewhere classified FOS: Biological sciences FOS: Earth and related environmental sciences FOS: Physical sciences Medicine Molecular Biology Neuroscience Physical Sciences not elsewhere classified Physiology |
| title | Additional file 3 of Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress |
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