Identification of new putative inhibitors of Mycobacterium tuberculosis 3-dehydroshikimate dehydratase from a combination of ligand- and structure-based and deep learning in silico approaches

The development of new drugs against Mycobacterium tuberculosis is an essential strategy for fighting drug resistance. Although 3-dehydroquinate dehydratase (MtDHQ) is known to be a highly relevant target for M. tuberculosis, current research shows new putative inhibitors of MtDHQ selected by a larg...

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Hauptverfasser:	de Souza, João Vítor Perez, Kioshima, Erika Seki, Murase, Letícia Sayuri, de Souza Lima, Diego, Seixas, Flavio Augusto Vicente, Maigret, Bernard, Cardoso, Rosilene Fressatti
Format:	Dataset
Sprache:	eng
Schlagworte:	Biochemistry Biological Sciences not elsewhere classified Biophysics Biotechnology Chemical Sciences not elsewhere classified FOS: Biological sciences FOS: Chemical sciences FOS: Computer and information sciences Information Systems not elsewhere classified Pharmacology
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