Additional file 12 of Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome
Additional file 11: Figure S6. Associations of ferritin-related transcripts with liver fat accumulation. a) Permutation tests for the goodness-of-fit (R2Y) and goodness of prediction (Q2Y) obtained from the O-PLS model between the liver fat accumulation degree and transcripts that were significantly...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Bild |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Mayneris-Perxachs, Jordi Cardellini, Marina Hoyles, Lesley Jèssica Latorre Davato, Francesca Moreno-Navarrete, José Maria Arnoriaga-Rodríguez, María Serino, Matteo Abbott, James Barton, Richard H. Puig, Josep Fernández-Real, Xavier Wifredo Ricart Tomlinson, Christopher Woodbridge, Mark Gentileschi, Paolo Butcher, Sarah A. Holmes, Elaine Nicholson, Jeremy K. Pérez-Brocal, Vicente Moya, Andrés Clain, Donald Mc Burcelin, Rémy Marc-Emmanuel Dumas Federici, Massimo José-Manuel Fernández-Real |
| description | Additional file 11: Figure S6. Associations of ferritin-related transcripts with liver fat accumulation. a) Permutation tests for the goodness-of-fit (R2Y) and goodness of prediction (Q2Y) obtained from the O-PLS model between the liver fat accumulation degree and transcripts that were significantly associated with serum ferritin. b) Significant transcripts associated with liver fat accumulation from O-PLS regression loadings. Hepatic genes belonging to the transcriptomic signature associated with serum ferritin and the gut microbiome are highlighted in dark red and blue. c) Further validation of O-PLS identified transcripts by pSC adjusting for age, BMI, sex, and country. d-g) Boxplots showing four hepatic genes identified in the transcriptomic signature associated with serum ferritin and the microbiome according to the serum ferritin quartiles (Q1-Q4). |
| doi_str_mv | 10.6084/m9.figshare.14558963 |
| format | Image |
| fullrecord | <record><control><sourceid>datacite_PQ8</sourceid><recordid>TN_cdi_datacite_primary_10_6084_m9_figshare_14558963</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_6084_m9_figshare_14558963</sourcerecordid><originalsourceid>FETCH-datacite_primary_10_6084_m9_figshare_145589633</originalsourceid><addsrcrecordid>eNqdjkFuwjAQRb3poqK9QRdzAdKkJIgsUdUK9uytwRknI9keZE8qcfsGCS7A6i3-f9Iz5qOpq229az9jX3key4SZqqbtul2_3bwa3Q8DK0vCAJ4DQfMF4uGYJUFR1LkAJx9mSo4KJElrDE4mCezAo-oVAv9RhoELYaHlDHKmwsugU5Z5nBYSjLNCZJflzBLpzbx4DIXe71yZ9vfn9H1YD6joWMleMkfMV9vU9hZvY28f8fYRv3lS-weNjloO</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>image</recordtype></control><display><type>image</type><title>Additional file 12 of Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome</title><source>DataCite</source><creator>Mayneris-Perxachs, Jordi ; Cardellini, Marina ; Hoyles, Lesley ; Jèssica Latorre ; Davato, Francesca ; Moreno-Navarrete, José Maria ; Arnoriaga-Rodríguez, María ; Serino, Matteo ; Abbott, James ; Barton, Richard H. ; Puig, Josep ; Fernández-Real, Xavier ; Wifredo Ricart ; Tomlinson, Christopher ; Woodbridge, Mark ; Gentileschi, Paolo ; Butcher, Sarah A. ; Holmes, Elaine ; Nicholson, Jeremy K. ; Pérez-Brocal, Vicente ; Moya, Andrés ; Clain, Donald Mc ; Burcelin, Rémy ; Marc-Emmanuel Dumas ; Federici, Massimo ; José-Manuel Fernández-Real</creator><creatorcontrib>Mayneris-Perxachs, Jordi ; Cardellini, Marina ; Hoyles, Lesley ; Jèssica Latorre ; Davato, Francesca ; Moreno-Navarrete, José Maria ; Arnoriaga-Rodríguez, María ; Serino, Matteo ; Abbott, James ; Barton, Richard H. ; Puig, Josep ; Fernández-Real, Xavier ; Wifredo Ricart ; Tomlinson, Christopher ; Woodbridge, Mark ; Gentileschi, Paolo ; Butcher, Sarah A. ; Holmes, Elaine ; Nicholson, Jeremy K. ; Pérez-Brocal, Vicente ; Moya, Andrés ; Clain, Donald Mc ; Burcelin, Rémy ; Marc-Emmanuel Dumas ; Federici, Massimo ; José-Manuel Fernández-Real</creatorcontrib><description>Additional file 11: Figure S6. Associations of ferritin-related transcripts with liver fat accumulation. a) Permutation tests for the goodness-of-fit (R2Y) and goodness of prediction (Q2Y) obtained from the O-PLS model between the liver fat accumulation degree and transcripts that were significantly associated with serum ferritin. b) Significant transcripts associated with liver fat accumulation from O-PLS regression loadings. Hepatic genes belonging to the transcriptomic signature associated with serum ferritin and the gut microbiome are highlighted in dark red and blue. c) Further validation of O-PLS identified transcripts by pSC adjusting for age, BMI, sex, and country. d-g) Boxplots showing four hepatic genes identified in the transcriptomic signature associated with serum ferritin and the microbiome according to the serum ferritin quartiles (Q1-Q4).</description><identifier>DOI: 10.6084/m9.figshare.14558963</identifier><language>eng</language><publisher>figshare</publisher><subject>Biochemistry ; Biotechnology ; Chemical Sciences not elsewhere classified ; FOS: Biological sciences ; FOS: Chemical sciences ; FOS: Health sciences ; Genetics ; Hematology ; Infectious Diseases ; Inorganic Chemistry ; Medicine ; Microbiology ; Physiology ; Virology</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>781,1895</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.6084/m9.figshare.14558963$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Mayneris-Perxachs, Jordi</creatorcontrib><creatorcontrib>Cardellini, Marina</creatorcontrib><creatorcontrib>Hoyles, Lesley</creatorcontrib><creatorcontrib>Jèssica Latorre</creatorcontrib><creatorcontrib>Davato, Francesca</creatorcontrib><creatorcontrib>Moreno-Navarrete, José Maria</creatorcontrib><creatorcontrib>Arnoriaga-Rodríguez, María</creatorcontrib><creatorcontrib>Serino, Matteo</creatorcontrib><creatorcontrib>Abbott, James</creatorcontrib><creatorcontrib>Barton, Richard H.</creatorcontrib><creatorcontrib>Puig, Josep</creatorcontrib><creatorcontrib>Fernández-Real, Xavier</creatorcontrib><creatorcontrib>Wifredo Ricart</creatorcontrib><creatorcontrib>Tomlinson, Christopher</creatorcontrib><creatorcontrib>Woodbridge, Mark</creatorcontrib><creatorcontrib>Gentileschi, Paolo</creatorcontrib><creatorcontrib>Butcher, Sarah A.</creatorcontrib><creatorcontrib>Holmes, Elaine</creatorcontrib><creatorcontrib>Nicholson, Jeremy K.</creatorcontrib><creatorcontrib>Pérez-Brocal, Vicente</creatorcontrib><creatorcontrib>Moya, Andrés</creatorcontrib><creatorcontrib>Clain, Donald Mc</creatorcontrib><creatorcontrib>Burcelin, Rémy</creatorcontrib><creatorcontrib>Marc-Emmanuel Dumas</creatorcontrib><creatorcontrib>Federici, Massimo</creatorcontrib><creatorcontrib>José-Manuel Fernández-Real</creatorcontrib><title>Additional file 12 of Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome</title><description>Additional file 11: Figure S6. Associations of ferritin-related transcripts with liver fat accumulation. a) Permutation tests for the goodness-of-fit (R2Y) and goodness of prediction (Q2Y) obtained from the O-PLS model between the liver fat accumulation degree and transcripts that were significantly associated with serum ferritin. b) Significant transcripts associated with liver fat accumulation from O-PLS regression loadings. Hepatic genes belonging to the transcriptomic signature associated with serum ferritin and the gut microbiome are highlighted in dark red and blue. c) Further validation of O-PLS identified transcripts by pSC adjusting for age, BMI, sex, and country. d-g) Boxplots showing four hepatic genes identified in the transcriptomic signature associated with serum ferritin and the microbiome according to the serum ferritin quartiles (Q1-Q4).</description><subject>Biochemistry</subject><subject>Biotechnology</subject><subject>Chemical Sciences not elsewhere classified</subject><subject>FOS: Biological sciences</subject><subject>FOS: Chemical sciences</subject><subject>FOS: Health sciences</subject><subject>Genetics</subject><subject>Hematology</subject><subject>Infectious Diseases</subject><subject>Inorganic Chemistry</subject><subject>Medicine</subject><subject>Microbiology</subject><subject>Physiology</subject><subject>Virology</subject><fulltext>true</fulltext><rsrctype>image</rsrctype><creationdate>2021</creationdate><recordtype>image</recordtype><sourceid>PQ8</sourceid><recordid>eNqdjkFuwjAQRb3poqK9QRdzAdKkJIgsUdUK9uytwRknI9keZE8qcfsGCS7A6i3-f9Iz5qOpq229az9jX3key4SZqqbtul2_3bwa3Q8DK0vCAJ4DQfMF4uGYJUFR1LkAJx9mSo4KJElrDE4mCezAo-oVAv9RhoELYaHlDHKmwsugU5Z5nBYSjLNCZJflzBLpzbx4DIXe71yZ9vfn9H1YD6joWMleMkfMV9vU9hZvY28f8fYRv3lS-weNjloO</recordid><startdate>20210508</startdate><enddate>20210508</enddate><creator>Mayneris-Perxachs, Jordi</creator><creator>Cardellini, Marina</creator><creator>Hoyles, Lesley</creator><creator>Jèssica Latorre</creator><creator>Davato, Francesca</creator><creator>Moreno-Navarrete, José Maria</creator><creator>Arnoriaga-Rodríguez, María</creator><creator>Serino, Matteo</creator><creator>Abbott, James</creator><creator>Barton, Richard H.</creator><creator>Puig, Josep</creator><creator>Fernández-Real, Xavier</creator><creator>Wifredo Ricart</creator><creator>Tomlinson, Christopher</creator><creator>Woodbridge, Mark</creator><creator>Gentileschi, Paolo</creator><creator>Butcher, Sarah A.</creator><creator>Holmes, Elaine</creator><creator>Nicholson, Jeremy K.</creator><creator>Pérez-Brocal, Vicente</creator><creator>Moya, Andrés</creator><creator>Clain, Donald Mc</creator><creator>Burcelin, Rémy</creator><creator>Marc-Emmanuel Dumas</creator><creator>Federici, Massimo</creator><creator>José-Manuel Fernández-Real</creator><general>figshare</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20210508</creationdate><title>Additional file 12 of Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome</title><author>Mayneris-Perxachs, Jordi ; Cardellini, Marina ; Hoyles, Lesley ; Jèssica Latorre ; Davato, Francesca ; Moreno-Navarrete, José Maria ; Arnoriaga-Rodríguez, María ; Serino, Matteo ; Abbott, James ; Barton, Richard H. ; Puig, Josep ; Fernández-Real, Xavier ; Wifredo Ricart ; Tomlinson, Christopher ; Woodbridge, Mark ; Gentileschi, Paolo ; Butcher, Sarah A. ; Holmes, Elaine ; Nicholson, Jeremy K. ; Pérez-Brocal, Vicente ; Moya, Andrés ; Clain, Donald Mc ; Burcelin, Rémy ; Marc-Emmanuel Dumas ; Federici, Massimo ; José-Manuel Fernández-Real</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_6084_m9_figshare_145589633</frbrgroupid><rsrctype>images</rsrctype><prefilter>images</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biochemistry</topic><topic>Biotechnology</topic><topic>Chemical Sciences not elsewhere classified</topic><topic>FOS: Biological sciences</topic><topic>FOS: Chemical sciences</topic><topic>FOS: Health sciences</topic><topic>Genetics</topic><topic>Hematology</topic><topic>Infectious Diseases</topic><topic>Inorganic Chemistry</topic><topic>Medicine</topic><topic>Microbiology</topic><topic>Physiology</topic><topic>Virology</topic><toplevel>online_resources</toplevel><creatorcontrib>Mayneris-Perxachs, Jordi</creatorcontrib><creatorcontrib>Cardellini, Marina</creatorcontrib><creatorcontrib>Hoyles, Lesley</creatorcontrib><creatorcontrib>Jèssica Latorre</creatorcontrib><creatorcontrib>Davato, Francesca</creatorcontrib><creatorcontrib>Moreno-Navarrete, José Maria</creatorcontrib><creatorcontrib>Arnoriaga-Rodríguez, María</creatorcontrib><creatorcontrib>Serino, Matteo</creatorcontrib><creatorcontrib>Abbott, James</creatorcontrib><creatorcontrib>Barton, Richard H.</creatorcontrib><creatorcontrib>Puig, Josep</creatorcontrib><creatorcontrib>Fernández-Real, Xavier</creatorcontrib><creatorcontrib>Wifredo Ricart</creatorcontrib><creatorcontrib>Tomlinson, Christopher</creatorcontrib><creatorcontrib>Woodbridge, Mark</creatorcontrib><creatorcontrib>Gentileschi, Paolo</creatorcontrib><creatorcontrib>Butcher, Sarah A.</creatorcontrib><creatorcontrib>Holmes, Elaine</creatorcontrib><creatorcontrib>Nicholson, Jeremy K.</creatorcontrib><creatorcontrib>Pérez-Brocal, Vicente</creatorcontrib><creatorcontrib>Moya, Andrés</creatorcontrib><creatorcontrib>Clain, Donald Mc</creatorcontrib><creatorcontrib>Burcelin, Rémy</creatorcontrib><creatorcontrib>Marc-Emmanuel Dumas</creatorcontrib><creatorcontrib>Federici, Massimo</creatorcontrib><creatorcontrib>José-Manuel Fernández-Real</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Mayneris-Perxachs, Jordi</au><au>Cardellini, Marina</au><au>Hoyles, Lesley</au><au>Jèssica Latorre</au><au>Davato, Francesca</au><au>Moreno-Navarrete, José Maria</au><au>Arnoriaga-Rodríguez, María</au><au>Serino, Matteo</au><au>Abbott, James</au><au>Barton, Richard H.</au><au>Puig, Josep</au><au>Fernández-Real, Xavier</au><au>Wifredo Ricart</au><au>Tomlinson, Christopher</au><au>Woodbridge, Mark</au><au>Gentileschi, Paolo</au><au>Butcher, Sarah A.</au><au>Holmes, Elaine</au><au>Nicholson, Jeremy K.</au><au>Pérez-Brocal, Vicente</au><au>Moya, Andrés</au><au>Clain, Donald Mc</au><au>Burcelin, Rémy</au><au>Marc-Emmanuel Dumas</au><au>Federici, Massimo</au><au>José-Manuel Fernández-Real</au><format>book</format><genre>unknown</genre><ristype>GEN</ristype><title>Additional file 12 of Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome</title><date>2021-05-08</date><risdate>2021</risdate><abstract>Additional file 11: Figure S6. Associations of ferritin-related transcripts with liver fat accumulation. a) Permutation tests for the goodness-of-fit (R2Y) and goodness of prediction (Q2Y) obtained from the O-PLS model between the liver fat accumulation degree and transcripts that were significantly associated with serum ferritin. b) Significant transcripts associated with liver fat accumulation from O-PLS regression loadings. Hepatic genes belonging to the transcriptomic signature associated with serum ferritin and the gut microbiome are highlighted in dark red and blue. c) Further validation of O-PLS identified transcripts by pSC adjusting for age, BMI, sex, and country. d-g) Boxplots showing four hepatic genes identified in the transcriptomic signature associated with serum ferritin and the microbiome according to the serum ferritin quartiles (Q1-Q4).</abstract><pub>figshare</pub><doi>10.6084/m9.figshare.14558963</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | DOI: 10.6084/m9.figshare.14558963 |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_datacite_primary_10_6084_m9_figshare_14558963 |
| source | DataCite |
| subjects | Biochemistry Biotechnology Chemical Sciences not elsewhere classified FOS: Biological sciences FOS: Chemical sciences FOS: Health sciences Genetics Hematology Infectious Diseases Inorganic Chemistry Medicine Microbiology Physiology Virology |
| title | Additional file 12 of Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T13%3A55%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-datacite_PQ8&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.au=Mayneris-Perxachs,%20Jordi&rft.date=2021-05-08&rft_id=info:doi/10.6084/m9.figshare.14558963&rft_dat=%3Cdatacite_PQ8%3E10_6084_m9_figshare_14558963%3C/datacite_PQ8%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |