Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice

The Suv39h1 and Suv39h2 H3K9 histone methyltransferases (HMTs) have a conserved role in the formation of constitutive heterochromatin and gene silencing. Using a transgenic mouse model system we demonstrate that elevated expression of Suv39h1 increases global H3K9me3 levels in vivo. More specificall...

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Bibliographische Detailangaben

Hauptverfasser:	Petti, Eleonora, Jordi, Fabian, Buemi, Valentina, Dinami, Roberto, Benetti, Roberta, Blasco, Maria A, Schoeftner, Stefan
Format:	Dataset
Sprache:	eng
Schlagworte:	Biotechnology Cancer Cell Biology Computational Biology Developmental Biology FOS: Biological sciences Genetics Molecular Biology
Online-Zugang:	Volltext bestellen
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