Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells

Selective targeting of cancer stem cells (CSCs), implicated in tumor relapse, holds great promise in the treatment of colorectal cancer. Overexpression of C-terminal binding protein (CtBP), an NADH dependent transcriptional regulator, is often observed in colon cancer. Of note, TCF-4 signaling is al...

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Hauptverfasser:	Jagrut Patel, Somesh Baranwal, Love, Ian M, Nirmita J Patel, Grossman, Steven R, Bhaumik B Patel
Format:	Dataset
Sprache:	eng
Schlagworte:	Biochemistry Biotechnology Cancer Cell Biology Chemistry Developmental Biology FOS: Biological sciences Medicine Microbiology Molecular Biology Pharmacology
Online-Zugang:	Volltext bestellen
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