Antisense regulation of co-transcriptional folding paths

Copyright information:Taken from "Encoding folding paths of RNA switches"Nucleic Acids Research 2006;35(2):614-622.Published online 18 Dec 2006PMCID:PMC1802593.© 2006 The Author(s). Interpretation of the encoded (left) and redirected (right) co-transcriptional folding paths of the reverse switch (Figure 4). This is based on simulations performed using the kinefold server () (), To simulate the effect of antisense interaction, the 7mer and RNA switch sequences are actually attached together via an inert linker (made of ‘X’ bases that do not pair).