Osteoporosis- and obesity-risk interrelationships: an epigenetic analysis of GWAS-derived SNPs at the developmental gene TBX15

A major challenge in translating findings from genome-wide association studies (GWAS) to biological mechanisms is pinpointing functional variants because only a very small percentage of variants associated with a given trait actually impact the trait. We used an extensive epigenetics, transcriptomic...

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Hauptverfasser: Zhang, Xiao, Ehrlich, Kenneth C., Yu, Fangtang, Hu, Xiaojun, Meng, Xiang-He, Deng, Hong-Wen, Shen, Hui, Ehrlich, Melanie
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Sprache:eng
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