Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption
Abstract INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were...
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creator | Ribeiro, Ághata Cardoso da Silva Crozatti, Márcia Terezinha Lonardoni Silva, Adilson Aderito da Macedo, Rodrigo Spineli Machado, Antonia Maria de Oliveira Silva, Antonio Távora de Albuquerque |
description | Abstract INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance. |
doi_str_mv | 10.6084/m9.figshare.11452968 |
format | Dataset |
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METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.</description><identifier>DOI: 10.6084/m9.figshare.11452968</identifier><language>eng</language><publisher>SciELO journals</publisher><subject>Medicine</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776,1888</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.6084/m9.figshare.11452968$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ribeiro, Ághata Cardoso da Silva</creatorcontrib><creatorcontrib>Crozatti, Márcia Terezinha Lonardoni</creatorcontrib><creatorcontrib>Silva, Adilson Aderito da</creatorcontrib><creatorcontrib>Macedo, Rodrigo Spineli</creatorcontrib><creatorcontrib>Machado, Antonia Maria de Oliveira</creatorcontrib><creatorcontrib>Silva, Antonio Távora de Albuquerque</creatorcontrib><title>Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption</title><description>Abstract INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. 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METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.</abstract><pub>SciELO journals</pub><doi>10.6084/m9.figshare.11452968</doi><oa>free_for_read</oa></addata></record> |
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title | Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption |
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