Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption

Abstract INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were...

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Hauptverfasser: Ribeiro, Ághata Cardoso da Silva, Crozatti, Márcia Terezinha Lonardoni, Silva, Adilson Aderito da, Macedo, Rodrigo Spineli, Machado, Antonia Maria de Oliveira, Silva, Antonio Távora de Albuquerque
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creator Ribeiro, Ághata Cardoso da Silva
Crozatti, Márcia Terezinha Lonardoni
Silva, Adilson Aderito da
Macedo, Rodrigo Spineli
Machado, Antonia Maria de Oliveira
Silva, Antonio Távora de Albuquerque
description Abstract INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.
doi_str_mv 10.6084/m9.figshare.11452968
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METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.</abstract><pub>SciELO journals</pub><doi>10.6084/m9.figshare.11452968</doi><oa>free_for_read</oa></addata></record>
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title Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption
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