Data and output files for the paper, "Dynamical systems inference at scale reveals intrinsic instability in the dysbiotic microbiome"

The above files contain the output of the model, which we call MDSINE2, developed in the paper titled, "Dynamical systems inference at scale reveals intrinsic instability in the dysbiotic microbiome" (See https://github.com/gerberlab/MDSINE2_Paper for implementation details). More specific...

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Hauptverfasser: Gibson, Travis E., Younhun Kim, Sawal Acharya, Kaplan, David, DiBenedetto, Nicholas, Lavin, Richard, Berger, Bonnie, Allegretti, Jessica, Bry, Lynn, Gerber, Georg
Format: Dataset
Sprache:eng
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Zusammenfassung:The above files contain the output of the model, which we call MDSINE2, developed in the paper titled, "Dynamical systems inference at scale reveals intrinsic instability in the dysbiotic microbiome" (See https://github.com/gerberlab/MDSINE2_Paper for implementation details). More specifically, forward_sims.tgz contains the output of forward simulations in .npy format; mixed_prior_fixed.tgz contains the pickle files corresponding to the output of the MCMC simulations for fixed topology; mixed_prior_unfixed.tgz contains the pickle files corresponding to the output of the MCMC simulations for unfixed topology; other_files contains information on eigenvalues and cycles, results for Phylogenetic Neighborhood Analysis, Keystoneness Analysis and the output in .npy format for comparator methods; ASV_OTU_aggregate_and_plylogeneteic trees contains the plots of trajectories (relative abundance) of OTUS and their constituent ASVs, and of phylogenetic trees.
DOI:10.5281/zenodo.5527256