SLC12A4/SLC12A6; A Target Enabling Package

KCC1 (SLC12A4) and KCC3 (SLC12A6) are co-transporters of potassium and chloride, and members of cation-chloride co-transporter (CCC; or Solute Carrier 12) family. They regulate chloride level and cell volume via export of potassium and chloride ions. KCC1 plays an important role in sickle cell disea...

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Bibliographische Detailangaben
Hauptverfasser:	Gamma Chi, Ebenhoch, Rebecca, Man, Henry, Haiping Tang, Tremblay, Laurence E., Reggiano, Gabriella, Xingyu Qiu, Bohstedt, Tina, Abrusci, Patrizia, Tehan, Ben, Liko, Idlir, Almeida, Fernando, Garneau, Alexandre P., Wang, Dong, McKinley, Gavin, Shubhashish M.M. Mukhopadhyay, Fernandez-Cid, Alejandra, Slimani, Samira, , Julie L. Lavoie, Burgess-Brown, Nicola, DiMaio, Frank, Isenring, Paul, Robinson, Carol V., Duerr, Katharina L.
Format:	Dataset
Sprache:	eng
Schlagworte:	Chemical Biology Disease Drug discovery Drug Target KCC1 KCC3 Orphan disease Probe Protein Sickle cell disease SLC12A4 SLC12A6 Structural Genomics Structure Structure Discovery Target Enabling Package
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