MYC-targeting by OMO-103 in solid tumours: a phase 1 trial

MYC is a ‘most wanted’ target in cancer therapy and it coordinates key transcriptional programs in tumour development and maintenance. It has, however, long been considered undruggable. OMO-103 is a MYC inhibitor consisting of a 91 amino acid mini-protein. Here we present results from a Phase 1 stud...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Soucek, Laura, Arques Casamitjana, Oriol, Casacuberta-Serra, Silvia, Martinez-Martin, Sandra, Foradada Felip, Laia, Masso-Valles, Daniel, Lopez-Estevez, Sergio, Jauset, Toni, Castillo Cano, Virginia, Morales, Josefa, Whitfield, Jonathan, Niewel, Manuela, Beaulieu, Marie-Eve, Garralda, Elena, Moreno, Victor, Alonzo, Guzman, Corral de la Fuente, Elena, Dodger, Bernard, Hernandez, Tatiana, Perez-Lopez, Raquel, Calvo, Emiliano
Format:	Dataset
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!