Data from: Effects of a multidisciplinary approach to improve volume of diagnostic material in CT-guided lung biopsies
Background: Recent publications have emphasized the importance of a multidisciplinary strategy for maximum conservation and utilization of lung biopsy material for advanced testing, which may determine therapy. This paper quantifies the effect of a multidisciplinary strategy implemented to optimize...
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| creator | Ferguson, Philip E. Sales, Catherine M. Hodges, Dalton C. Sales, Elizabeth W. |
| description | Background: Recent publications have emphasized the importance of a
multidisciplinary strategy for maximum conservation and utilization of
lung biopsy material for advanced testing, which may determine therapy.
This paper quantifies the effect of a multidisciplinary strategy
implemented to optimize and increase tissue volume in CT-guided
transthoracic needle core lung biopsies. The strategy was three-pronged:
(1) once there was confidence diagnostic tissue had been obtained and if
safe for the patient, additional biopsy passes were performed to further
increase volume of biopsy material, (2) biopsy material was placed in
multiple cassettes for processing, and (3) all tissue ribbons were
conserved when cutting blocks in the histology laboratory. This study
quantifies the effects of strategies #1 and #2. Design: This retrospective
analysis comparing CT-guided lung biopsies from 2007 and 2012 (before and
after multidisciplinary approach implementation) was performed at a single
institution. Patient medical records were reviewed and main variables
analyzed include biopsy sample size, radiologist, number of blocks
submitted, diagnosis, and complications. The biopsy sample size measured
was considered to be directly proportional to tissue volume in the block.
Results: Biopsy sample size increased 2.5 fold with the average total
biopsy sample size increasing from 1.0 cm (0.9–1.1 cm) in 2007 to 2.5 cm
(2.3–2.8 cm) in 2012 (P |
| doi_str_mv | 10.5061/dryad.6bt21 |
| format | Dataset |
| fullrecord | <record><control><sourceid>datacite_PQ8</sourceid><recordid>TN_cdi_datacite_primary_10_5061_dryad_6bt21</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_5061_dryad_6bt21</sourcerecordid><originalsourceid>FETCH-datacite_primary_10_5061_dryad_6bt213</originalsourceid><addsrcrecordid>eNqVzk0OgjAQBeBuXBh15QVmb0DQyMItYjwA-2bsD07S0qYtJNxeIF7A1bzFvLyPsWNZ5LeiKs8yTCjz6p0u5ZaND0wIOjh7h0ZrJVIEpwHBDiaRpCjIG-oxTIDeB4fiA8kB2TmPCkZnBquWhiTsehcTCbCYVCA0QD3UbdYNJJUEM_QdvMn5SCru2Uajierwuzt2ejZt_crkzBGUFPeB7LzKy4Ivar6q-aq-_vf9BeamU2w</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>dataset</recordtype></control><display><type>dataset</type><title>Data from: Effects of a multidisciplinary approach to improve volume of diagnostic material in CT-guided lung biopsies</title><source>DataCite</source><creator>Ferguson, Philip E. ; Sales, Catherine M. ; Hodges, Dalton C. ; Sales, Elizabeth W.</creator><creatorcontrib>Ferguson, Philip E. ; Sales, Catherine M. ; Hodges, Dalton C. ; Sales, Elizabeth W.</creatorcontrib><description>Background: Recent publications have emphasized the importance of a
multidisciplinary strategy for maximum conservation and utilization of
lung biopsy material for advanced testing, which may determine therapy.
This paper quantifies the effect of a multidisciplinary strategy
implemented to optimize and increase tissue volume in CT-guided
transthoracic needle core lung biopsies. The strategy was three-pronged:
(1) once there was confidence diagnostic tissue had been obtained and if
safe for the patient, additional biopsy passes were performed to further
increase volume of biopsy material, (2) biopsy material was placed in
multiple cassettes for processing, and (3) all tissue ribbons were
conserved when cutting blocks in the histology laboratory. This study
quantifies the effects of strategies #1 and #2. Design: This retrospective
analysis comparing CT-guided lung biopsies from 2007 and 2012 (before and
after multidisciplinary approach implementation) was performed at a single
institution. Patient medical records were reviewed and main variables
analyzed include biopsy sample size, radiologist, number of blocks
submitted, diagnosis, and complications. The biopsy sample size measured
was considered to be directly proportional to tissue volume in the block.
Results: Biopsy sample size increased 2.5 fold with the average total
biopsy sample size increasing from 1.0 cm (0.9–1.1 cm) in 2007 to 2.5 cm
(2.3–2.8 cm) in 2012 (P<0.0001). The improvement was statistically
significant for each individual radiologist. During the same time, the
rate of pneumothorax requiring chest tube placement decreased from 15% to
7% (P = 0.065). No other major complications were identified. The
proportion of tumor within the biopsy material was similar at 28%
(23%–33%) and 35% (30%–40%) for 2007 and 2012, respectively. The number of
cases with at least two blocks available for testing increased from 10.7%
to 96.4% (P<0.0001). Conclusions: The effect of this
multidisciplinary strategy to CT-guided lung biopsies was effective in
significantly increasing tissue volume and number of blocks available for
advanced diagnostic testing.</description><identifier>DOI: 10.5061/dryad.6bt21</identifier><language>eng</language><publisher>Dryad</publisher><subject>biopsy adequacy ; CT-guided lung biopsy ; lung biopsy ; Lung cancer ; multidisciplinary strategy ; tissue biopsy volume ; tumor volume</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776,1887</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.5061/dryad.6bt21$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ferguson, Philip E.</creatorcontrib><creatorcontrib>Sales, Catherine M.</creatorcontrib><creatorcontrib>Hodges, Dalton C.</creatorcontrib><creatorcontrib>Sales, Elizabeth W.</creatorcontrib><title>Data from: Effects of a multidisciplinary approach to improve volume of diagnostic material in CT-guided lung biopsies</title><description>Background: Recent publications have emphasized the importance of a
multidisciplinary strategy for maximum conservation and utilization of
lung biopsy material for advanced testing, which may determine therapy.
This paper quantifies the effect of a multidisciplinary strategy
implemented to optimize and increase tissue volume in CT-guided
transthoracic needle core lung biopsies. The strategy was three-pronged:
(1) once there was confidence diagnostic tissue had been obtained and if
safe for the patient, additional biopsy passes were performed to further
increase volume of biopsy material, (2) biopsy material was placed in
multiple cassettes for processing, and (3) all tissue ribbons were
conserved when cutting blocks in the histology laboratory. This study
quantifies the effects of strategies #1 and #2. Design: This retrospective
analysis comparing CT-guided lung biopsies from 2007 and 2012 (before and
after multidisciplinary approach implementation) was performed at a single
institution. Patient medical records were reviewed and main variables
analyzed include biopsy sample size, radiologist, number of blocks
submitted, diagnosis, and complications. The biopsy sample size measured
was considered to be directly proportional to tissue volume in the block.
Results: Biopsy sample size increased 2.5 fold with the average total
biopsy sample size increasing from 1.0 cm (0.9–1.1 cm) in 2007 to 2.5 cm
(2.3–2.8 cm) in 2012 (P<0.0001). The improvement was statistically
significant for each individual radiologist. During the same time, the
rate of pneumothorax requiring chest tube placement decreased from 15% to
7% (P = 0.065). No other major complications were identified. The
proportion of tumor within the biopsy material was similar at 28%
(23%–33%) and 35% (30%–40%) for 2007 and 2012, respectively. The number of
cases with at least two blocks available for testing increased from 10.7%
to 96.4% (P<0.0001). Conclusions: The effect of this
multidisciplinary strategy to CT-guided lung biopsies was effective in
significantly increasing tissue volume and number of blocks available for
advanced diagnostic testing.</description><subject>biopsy adequacy</subject><subject>CT-guided lung biopsy</subject><subject>lung biopsy</subject><subject>Lung cancer</subject><subject>multidisciplinary strategy</subject><subject>tissue biopsy volume</subject><subject>tumor volume</subject><fulltext>true</fulltext><rsrctype>dataset</rsrctype><creationdate>2015</creationdate><recordtype>dataset</recordtype><sourceid>PQ8</sourceid><recordid>eNqVzk0OgjAQBeBuXBh15QVmb0DQyMItYjwA-2bsD07S0qYtJNxeIF7A1bzFvLyPsWNZ5LeiKs8yTCjz6p0u5ZaND0wIOjh7h0ZrJVIEpwHBDiaRpCjIG-oxTIDeB4fiA8kB2TmPCkZnBquWhiTsehcTCbCYVCA0QD3UbdYNJJUEM_QdvMn5SCru2Uajierwuzt2ejZt_crkzBGUFPeB7LzKy4Ivar6q-aq-_vf9BeamU2w</recordid><startdate>20151023</startdate><enddate>20151023</enddate><creator>Ferguson, Philip E.</creator><creator>Sales, Catherine M.</creator><creator>Hodges, Dalton C.</creator><creator>Sales, Elizabeth W.</creator><general>Dryad</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20151023</creationdate><title>Data from: Effects of a multidisciplinary approach to improve volume of diagnostic material in CT-guided lung biopsies</title><author>Ferguson, Philip E. ; Sales, Catherine M. ; Hodges, Dalton C. ; Sales, Elizabeth W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_5061_dryad_6bt213</frbrgroupid><rsrctype>datasets</rsrctype><prefilter>datasets</prefilter><language>eng</language><creationdate>2015</creationdate><topic>biopsy adequacy</topic><topic>CT-guided lung biopsy</topic><topic>lung biopsy</topic><topic>Lung cancer</topic><topic>multidisciplinary strategy</topic><topic>tissue biopsy volume</topic><topic>tumor volume</topic><toplevel>online_resources</toplevel><creatorcontrib>Ferguson, Philip E.</creatorcontrib><creatorcontrib>Sales, Catherine M.</creatorcontrib><creatorcontrib>Hodges, Dalton C.</creatorcontrib><creatorcontrib>Sales, Elizabeth W.</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ferguson, Philip E.</au><au>Sales, Catherine M.</au><au>Hodges, Dalton C.</au><au>Sales, Elizabeth W.</au><format>book</format><genre>unknown</genre><ristype>DATA</ristype><title>Data from: Effects of a multidisciplinary approach to improve volume of diagnostic material in CT-guided lung biopsies</title><date>2015-10-23</date><risdate>2015</risdate><abstract>Background: Recent publications have emphasized the importance of a
multidisciplinary strategy for maximum conservation and utilization of
lung biopsy material for advanced testing, which may determine therapy.
This paper quantifies the effect of a multidisciplinary strategy
implemented to optimize and increase tissue volume in CT-guided
transthoracic needle core lung biopsies. The strategy was three-pronged:
(1) once there was confidence diagnostic tissue had been obtained and if
safe for the patient, additional biopsy passes were performed to further
increase volume of biopsy material, (2) biopsy material was placed in
multiple cassettes for processing, and (3) all tissue ribbons were
conserved when cutting blocks in the histology laboratory. This study
quantifies the effects of strategies #1 and #2. Design: This retrospective
analysis comparing CT-guided lung biopsies from 2007 and 2012 (before and
after multidisciplinary approach implementation) was performed at a single
institution. Patient medical records were reviewed and main variables
analyzed include biopsy sample size, radiologist, number of blocks
submitted, diagnosis, and complications. The biopsy sample size measured
was considered to be directly proportional to tissue volume in the block.
Results: Biopsy sample size increased 2.5 fold with the average total
biopsy sample size increasing from 1.0 cm (0.9–1.1 cm) in 2007 to 2.5 cm
(2.3–2.8 cm) in 2012 (P<0.0001). The improvement was statistically
significant for each individual radiologist. During the same time, the
rate of pneumothorax requiring chest tube placement decreased from 15% to
7% (P = 0.065). No other major complications were identified. The
proportion of tumor within the biopsy material was similar at 28%
(23%–33%) and 35% (30%–40%) for 2007 and 2012, respectively. The number of
cases with at least two blocks available for testing increased from 10.7%
to 96.4% (P<0.0001). Conclusions: The effect of this
multidisciplinary strategy to CT-guided lung biopsies was effective in
significantly increasing tissue volume and number of blocks available for
advanced diagnostic testing.</abstract><pub>Dryad</pub><doi>10.5061/dryad.6bt21</doi><oa>free_for_read</oa></addata></record> |
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| identifier | DOI: 10.5061/dryad.6bt21 |
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| recordid | cdi_datacite_primary_10_5061_dryad_6bt21 |
| source | DataCite |
| subjects | biopsy adequacy CT-guided lung biopsy lung biopsy Lung cancer multidisciplinary strategy tissue biopsy volume tumor volume |
| title | Data from: Effects of a multidisciplinary approach to improve volume of diagnostic material in CT-guided lung biopsies |
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