Phactboost Predictions

Most algorithms that are used to predict the effects of variants rely on evolutionary conservation. However, a majority of such techniques compute evolutionary conservation by solely using the alignment of multiple sequences while overlooking the evolutionary context of substitution events. We had i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Kuru, Nurdan, Dereli, Onur, Akkoyun, Emrah, Bircan, Aylin, Oznur Tastan, Adebali, Ogün
Format:	Dataset
Sprache:	eng
Schlagworte:	missense mutations mutation effect prediction PHACT PHCTboost phylogenetics protein sequences
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!