Supplementary Table 1: Urine-based regenerative RNA biomarkers for urinary bladder wound healing
Supplement Table 1. The expression of genes in morning and evening Abstract Background: This study aimed to investigate the expression of regeneration-related genes in canine urine during bladder repair. Materials & methods: Canine urine samples were collected after partial cystectomy. Regenerat...
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| creator | Yi, Xianlin Liu, Chanzhen Zhou, Juan Li, You Lu, Haoyuan Lu, Yulei Wei, Wei Wu, Mingsong |
| description | Supplement Table 1.
The expression of genes in morning and evening
Abstract
Background: This study aimed to investigate the expression of regeneration-related
genes in canine urine during bladder repair. Materials & methods:
Canine urine samples were collected after partial cystectomy. Regenerative mRNA
of hypoxia-inducible factor (HIF), vascular endothelial growth factor (VEGF),
key stem cell transcription factors, and cholinergic signals were detected. Results:
HIF-1α, VEGF, CD44, interleukin-6, and prominin 1 expression in canine urine
after partial cystectomy exhibited two similar peaks at ~2 weeks. HIF-1α and
VEGF expression was higher in the afternoon than in the morning. The expression
of key stem cell transcription factors and cholinergic signals also exhibited a
rhythm along with bladder healing. Conclusions: The expression of
HIF-1α, VEGF, key stem cell transcription factors, and cholinergic signals
exhibited a time curve distribution during canine bladder healing. The
expression trend of some regenerative genes was similar during bladder healing,
and a cooperative effect may exist. |
| doi_str_mv | 10.25402/rme.15090144 |
| format | Dataset |
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The expression of genes in morning and evening
Abstract
Background: This study aimed to investigate the expression of regeneration-related
genes in canine urine during bladder repair. Materials & methods:
Canine urine samples were collected after partial cystectomy. Regenerative mRNA
of hypoxia-inducible factor (HIF), vascular endothelial growth factor (VEGF),
key stem cell transcription factors, and cholinergic signals were detected. Results:
HIF-1α, VEGF, CD44, interleukin-6, and prominin 1 expression in canine urine
after partial cystectomy exhibited two similar peaks at ~2 weeks. HIF-1α and
VEGF expression was higher in the afternoon than in the morning. The expression
of key stem cell transcription factors and cholinergic signals also exhibited a
rhythm along with bladder healing. Conclusions: The expression of
HIF-1α, VEGF, key stem cell transcription factors, and cholinergic signals
exhibited a time curve distribution during canine bladder healing. The
expression trend of some regenerative genes was similar during bladder healing,
and a cooperative effect may exist.</description><identifier>DOI: 10.25402/rme.15090144</identifier><language>eng</language><publisher>Taylor & Francis</publisher><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,1892</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.25402/rme.15090144$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Yi, Xianlin</creatorcontrib><creatorcontrib>Liu, Chanzhen</creatorcontrib><creatorcontrib>Zhou, Juan</creatorcontrib><creatorcontrib>Li, You</creatorcontrib><creatorcontrib>Lu, Haoyuan</creatorcontrib><creatorcontrib>Lu, Yulei</creatorcontrib><creatorcontrib>Wei, Wei</creatorcontrib><creatorcontrib>Wu, Mingsong</creatorcontrib><title>Supplementary Table 1: Urine-based regenerative RNA biomarkers for urinary bladder wound healing</title><description>Supplement Table 1.
The expression of genes in morning and evening
Abstract
Background: This study aimed to investigate the expression of regeneration-related
genes in canine urine during bladder repair. Materials & methods:
Canine urine samples were collected after partial cystectomy. Regenerative mRNA
of hypoxia-inducible factor (HIF), vascular endothelial growth factor (VEGF),
key stem cell transcription factors, and cholinergic signals were detected. Results:
HIF-1α, VEGF, CD44, interleukin-6, and prominin 1 expression in canine urine
after partial cystectomy exhibited two similar peaks at ~2 weeks. HIF-1α and
VEGF expression was higher in the afternoon than in the morning. The expression
of key stem cell transcription factors and cholinergic signals also exhibited a
rhythm along with bladder healing. Conclusions: The expression of
HIF-1α, VEGF, key stem cell transcription factors, and cholinergic signals
exhibited a time curve distribution during canine bladder healing. The
expression trend of some regenerative genes was similar during bladder healing,
and a cooperative effect may exist.</description><fulltext>true</fulltext><rsrctype>dataset</rsrctype><creationdate>2021</creationdate><recordtype>dataset</recordtype><sourceid>PQ8</sourceid><recordid>eNqVjrEOgjAURbs4GHV0fz8AtgqDbsZonBwU5_qwD2wshTxAw9-LRj_A6S7nnhwhpkqG8ziS8xkXFKpYLqWKoqG4nNqqclSQb5A7SDB1BGoFZ7aeghRrMsCUkyfGxj4Ijoc1pLYskO_ENWQlQ9uz73Pq0BhieJatN3AjdNbnYzHI0NU0-e5IBLttstkHBhu82oZ0xba3dVpJ_SnUfaH-FS7-5V8BREnB</recordid><startdate>20210802</startdate><enddate>20210802</enddate><creator>Yi, Xianlin</creator><creator>Liu, Chanzhen</creator><creator>Zhou, Juan</creator><creator>Li, You</creator><creator>Lu, Haoyuan</creator><creator>Lu, Yulei</creator><creator>Wei, Wei</creator><creator>Wu, Mingsong</creator><general>Taylor & Francis</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20210802</creationdate><title>Supplementary Table 1: Urine-based regenerative RNA biomarkers for urinary bladder wound healing</title><author>Yi, Xianlin ; Liu, Chanzhen ; Zhou, Juan ; Li, You ; Lu, Haoyuan ; Lu, Yulei ; Wei, Wei ; Wu, Mingsong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_25402_rme_150901443</frbrgroupid><rsrctype>datasets</rsrctype><prefilter>datasets</prefilter><language>eng</language><creationdate>2021</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Yi, Xianlin</creatorcontrib><creatorcontrib>Liu, Chanzhen</creatorcontrib><creatorcontrib>Zhou, Juan</creatorcontrib><creatorcontrib>Li, You</creatorcontrib><creatorcontrib>Lu, Haoyuan</creatorcontrib><creatorcontrib>Lu, Yulei</creatorcontrib><creatorcontrib>Wei, Wei</creatorcontrib><creatorcontrib>Wu, Mingsong</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Yi, Xianlin</au><au>Liu, Chanzhen</au><au>Zhou, Juan</au><au>Li, You</au><au>Lu, Haoyuan</au><au>Lu, Yulei</au><au>Wei, Wei</au><au>Wu, Mingsong</au><format>book</format><genre>unknown</genre><ristype>DATA</ristype><title>Supplementary Table 1: Urine-based regenerative RNA biomarkers for urinary bladder wound healing</title><date>2021-08-02</date><risdate>2021</risdate><abstract>Supplement Table 1.
The expression of genes in morning and evening
Abstract
Background: This study aimed to investigate the expression of regeneration-related
genes in canine urine during bladder repair. Materials & methods:
Canine urine samples were collected after partial cystectomy. Regenerative mRNA
of hypoxia-inducible factor (HIF), vascular endothelial growth factor (VEGF),
key stem cell transcription factors, and cholinergic signals were detected. Results:
HIF-1α, VEGF, CD44, interleukin-6, and prominin 1 expression in canine urine
after partial cystectomy exhibited two similar peaks at ~2 weeks. HIF-1α and
VEGF expression was higher in the afternoon than in the morning. The expression
of key stem cell transcription factors and cholinergic signals also exhibited a
rhythm along with bladder healing. Conclusions: The expression of
HIF-1α, VEGF, key stem cell transcription factors, and cholinergic signals
exhibited a time curve distribution during canine bladder healing. The
expression trend of some regenerative genes was similar during bladder healing,
and a cooperative effect may exist.</abstract><pub>Taylor & Francis</pub><doi>10.25402/rme.15090144</doi><oa>free_for_read</oa></addata></record> |
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| title | Supplementary Table 1: Urine-based regenerative RNA biomarkers for urinary bladder wound healing |
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