Non-culture-based studies of the appendiceal microbiota: a systematic review - Methods-Reporting-Checklist_FM
Aims: To review studies examining the appendiceal microbiota and microbial changes in acute appendicitis. Methods: After a systematic literature search, 11 studies examining the appendiceal microbiota (414 samples) using non-culture-based methods were included. Results: The appendiceal microbiota sh...
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| creator | Antonsen, Jacob Winther-Jensen, Matilde Krogsbøll, Lasse T Jess, Tine Jorgensen, Lars N Allin, Kristine H |
| description | Aims: To review studies examining the appendiceal microbiota and microbial changes in acute
appendicitis. Methods: After a systematic literature search, 11 studies examining the appendiceal microbiota (414 samples) using non-culture-based methods were included. Results: The appendiceal microbiota showed decreased α-diversity compared with fecal microbiota. Inflamed and uninflamed appendices showed differences in β-diversity, and there was an increased abundance of oral-associated bacteria in inflamed versus uninflamed appendices. Conclusion: The appendiceal microbiota exhibits lower α-diversity than the fecal microbiota, with an increased abundance of oral-associated bacteria. Compared with uninflamed appendices, the appendix microbiota in acute appendicitis also showed increased abundance of oral-associated bacteria, but no bacterial profile unique to either complicated or uncomplicated appendicitis was found. |
| doi_str_mv | 10.25402/fmb.22269655 |
| format | Dataset |
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| title | Non-culture-based studies of the appendiceal microbiota: a systematic review - Methods-Reporting-Checklist_FM |
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