ATVB presentation 5-10-2019.pptx

Hmg-CoA Reductase (Hmgcr) catalyzes the conversion of Hmg-CoA to mevalonate, which is the rate-limiting step in the cholesterol biosynthetic pathway. Hmgcr is the target of statins, which are the front line therapy for hypercholesterolemia. In addition to cholesterol, Hmgcr activity is also required...

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Hauptverfasser:	De Giorgi, Marco, Jarrett, Kelsey, Burton, Jason, Doerfler, Alexandria, Hurley, Ayrea, Li, Ang, Hsu, Rachel, Furgurson, Mia N., Han, Jun, Borchers, Christoph H., R. Lagor, William
Format:	Video
Sprache:	eng
Schlagworte:	Cell metabolism
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