PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP dependent lipid uptake and fatty acid synthesis pathways
To gain a deeper understanding the role of PHLPP1 in lipid metabolism in macrophages, we performed mRNA Seq analysis to assess the gene expression changes in PHLPP1 knockdown RAW 264.7 cells treated with 100 microgram/ml of oxidized LDL for 24 h or left untreated. Sample defiintion: CTRL sh-Luc nucl...
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