Mineralocorticoid Receptor signaling emerges as a key mediator of Carfilzomib induced increase in blood pressure. Prophylactic potential of Eplerenone
Introduction: Carfilzomib (Carfilzomib), is a first-line irreversible proteasome inhibitor indicated for relapsed/refractory multiple myeloma, presenting life-threatening cardiovascular adverse effects. Hypertension, is the commonest side effect of Carfilzomib, remaining of unknown pathogenicity. Pu...
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