Influence of whole-body hyperthermia on mRNA expression in PBMCs from ME/CFS patients
These data show the measurement of mRNA expression in human PBMCs. The mRNA expression was measured in ME/CFS patients before and after whole-body hyperthermia treatment (1 hour at 39 °C). The following files show the Ct values of mRNA expression of the genes RPLP0, beta-actin, ULK1, Beclin 1, AMPK1...
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description | These data show the measurement of mRNA expression in human PBMCs. The mRNA expression was measured in ME/CFS patients before and after whole-body hyperthermia treatment (1 hour at 39 °C). The following files show the Ct values of mRNA expression of the genes RPLP0, beta-actin, ULK1, Beclin 1, AMPK1α, ATG7, FOXO3, HSPA5, IL-10, MAP1LC3B, SIRT1, SIRT3, TFAM, NDUFS1 and SOD2. The n-fold gene expression after calculation with the 2-ΔΔCt method shows a significant decrease in SIRT3 expression as a result of whole-body hyperthermia. Some other genes show slight but not significant changes. |
doi_str_mv | 10.17632/hyg3f3p6hd.1 |
format | Dataset |
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The mRNA expression was measured in ME/CFS patients before and after whole-body hyperthermia treatment (1 hour at 39 °C). The following files show the Ct values of mRNA expression of the genes RPLP0, beta-actin, ULK1, Beclin 1, AMPK1α, ATG7, FOXO3, HSPA5, IL-10, MAP1LC3B, SIRT1, SIRT3, TFAM, NDUFS1 and SOD2. The n-fold gene expression after calculation with the 2-ΔΔCt method shows a significant decrease in SIRT3 expression as a result of whole-body hyperthermia. Some other genes show slight but not significant changes.</description><identifier>DOI: 10.17632/hyg3f3p6hd.1</identifier><language>eng</language><publisher>Mendeley Data</publisher><subject>Gene Expression ; Hyperthermia</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,1894</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.17632/hyg3f3p6hd.1$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Hochecker, Barbara</creatorcontrib><title>Influence of whole-body hyperthermia on mRNA expression in PBMCs from ME/CFS patients</title><description>These data show the measurement of mRNA expression in human PBMCs. The mRNA expression was measured in ME/CFS patients before and after whole-body hyperthermia treatment (1 hour at 39 °C). The following files show the Ct values of mRNA expression of the genes RPLP0, beta-actin, ULK1, Beclin 1, AMPK1α, ATG7, FOXO3, HSPA5, IL-10, MAP1LC3B, SIRT1, SIRT3, TFAM, NDUFS1 and SOD2. The n-fold gene expression after calculation with the 2-ΔΔCt method shows a significant decrease in SIRT3 expression as a result of whole-body hyperthermia. Some other genes show slight but not significant changes.</description><subject>Gene Expression</subject><subject>Hyperthermia</subject><fulltext>true</fulltext><rsrctype>dataset</rsrctype><creationdate>2024</creationdate><recordtype>dataset</recordtype><sourceid>PQ8</sourceid><recordid>eNqVjrsKwjAUQLM4iDq63x_oIxbqrKVFB0V8zCG2NybQPEgi2r9XRHB2Ohw4wyFkTvOULstikcnhVojClbJL6Zhctkb0dzQtghXwkLbH5Gq7AeTg0EeJXisO1oA-7leAT-cxBPV2ZeCw3lUBhLcadnVWNSdwPCo0MUzJSPA-4OzLCUma-lxtko5H3qqIzHmluR8Yzdlni_22GC3-7V_4zUdD</recordid><startdate>20240727</startdate><enddate>20240727</enddate><creator>Hochecker, Barbara</creator><general>Mendeley Data</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20240727</creationdate><title>Influence of whole-body hyperthermia on mRNA expression in PBMCs from ME/CFS patients</title><author>Hochecker, Barbara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_17632_hyg3f3p6hd_13</frbrgroupid><rsrctype>datasets</rsrctype><prefilter>datasets</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Gene Expression</topic><topic>Hyperthermia</topic><toplevel>online_resources</toplevel><creatorcontrib>Hochecker, Barbara</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Hochecker, Barbara</au><format>book</format><genre>unknown</genre><ristype>DATA</ristype><title>Influence of whole-body hyperthermia on mRNA expression in PBMCs from ME/CFS patients</title><date>2024-07-27</date><risdate>2024</risdate><abstract>These data show the measurement of mRNA expression in human PBMCs. The mRNA expression was measured in ME/CFS patients before and after whole-body hyperthermia treatment (1 hour at 39 °C). The following files show the Ct values of mRNA expression of the genes RPLP0, beta-actin, ULK1, Beclin 1, AMPK1α, ATG7, FOXO3, HSPA5, IL-10, MAP1LC3B, SIRT1, SIRT3, TFAM, NDUFS1 and SOD2. The n-fold gene expression after calculation with the 2-ΔΔCt method shows a significant decrease in SIRT3 expression as a result of whole-body hyperthermia. Some other genes show slight but not significant changes.</abstract><pub>Mendeley Data</pub><doi>10.17632/hyg3f3p6hd.1</doi><oa>free_for_read</oa></addata></record> |
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subjects | Gene Expression Hyperthermia |
title | Influence of whole-body hyperthermia on mRNA expression in PBMCs from ME/CFS patients |
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