Interleukin-17 pathway inhibition with brodalumab in early systemic sclerosis: analysis of a single-arm, open-label, phase 1 trial
Systemic sclerosis (SSc) is an autoimmune disease that causes fibrosis of the skin and internal organs. Despite several studies reporting the role of interleukin-17 (IL-17) in SSc, no consensus exists regarding the role of the IL-17 pathway in SSc pathogenesis and progression. We hypothesize a possi...
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