Stereoselectivity of Proline-Cyclobutane amino acid-containing peptide organocatalysts for asymmetric aldol additions : A rationale

Several α,β,α- or α,γ,α-tripeptides, consisting of a central cyclobutane β- or γ-amino acid being flanked by two d- or l-proline residues, have been synthesized and tested as organocatalysts in asymmetric aldol additions. High yields and enantioselectivities have been achieved with α,γ,α-tripeptides...

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Hauptverfasser: Illa, Ona, Porcar-Tost, Oriol, Robledillo, Carme, Elvira, Carlos, Nolis Fañanas, Pau, Reiser, Oliver, Branchadell Gallo, Vicenç, Ortuño Mingarro, Rosa María
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Sprache:eng
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