BRCA1 mutations in high-grade serous ovarian cancer are associated with proteomic changes in DNA repair, splicing, transcription regulation and signaling

Despite recent advances in the management of BRCA1 mutated high-grade serous ovarian cancer (HGSC), the physiology of these tumors remains poorly understood. Here we provide a comprehensive molecular understanding of the signaling processes that drive HGSC pathogenesis with the addition of valuable...

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Hauptverfasser:	Bradbury, Melissa, Castellvi, Josep, Méndez Fernández, Olga, Sanchez Iglesias, Jose Luis, Pérez-Benavente, Assumpció, Gil-Moreno, Antonio, Sabidó, Eduard, Santamaría, Anna, Borràs, Eva, Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca (VHIR)
Format:	Artikel
Sprache:	eng
Schlagworte:	Ovarian cancer Proteomics
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