The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity

Ion channels are well placed to transduce environmental cues into signals used by cells to generate a wide range of responses, but little is known about their role in the regulation of RNA metabolism. Here we show that the TRPV4 cation channel binds the DEAD-box RNA helicase DDX3X and regulates its...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Doñate-Macian, Pablo, Jungfleisch, J, Pérez-Vilaró, Gemma, Rubio-Moscardo, F, Peralvarez-Marin, Alex, Diez, J, Valverde, M. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Ion channel signalling Viral infection
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