Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration

Synapse degeneration is an early event in pathological frontotemporal lobar degeneration (FTLD). Consequently, a surrogate marker of synapse loss could be used to monitor early pathologic changes in patients with underlying FTLD. The aim of this study was to evaluate the relationship of antemortem c...

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Hauptverfasser:	Cervantes González, Alba, Irwin, David J, Alcolea, Daniel, McMillan, Corey T, Chen-Plotkin, Alice, Wolk, David, Sirisi Dolcet, Sonia, Dols Icardo, Oriol, Querol-Vilaseca, Marta, Illán-Gala, Ignacio, Santos-Santos, Miguel Angel, Fortea, Juan, Lee, Edward B, Trojanowski, John Q, Grossman, Murray, Lleó, Alberto, Belbin, Olivia, Universitat Autònoma de Barcelona
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarker Calsyntenin-1 Cerebrospinal fluid Frontotemporal dementia Frontotemporal lobar degeneration Tau TDP-43
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