Enantioselective approach to indolizidine and quinolizidine scaffolds : application to the synthesis of peptide mimics
An enantioselective approach to substituted indolizidine and quinolizidine frameworks has been developed. Key steps of the synthesis are the enantioselective, palladium-catalyzed N-allylation of an imide, the nucleophilic allylation of an acyliminium ion and a ring closing metathesis. This general s...
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