Transfer to the Local Stroke Center versus Direct Transfer to Endovascular Center of Acute Stroke Patients with Suspected Large Vessel Occlusion in the Catalan Territory (RACECAT): Study protocol of a cluster randomized within a cohort trial
Rationale Optimal pre-hospital delivery pathways for acute stroke patients suspected to harbor a large vessel occlusion have not been assessed in randomized trials. Aim To establish whether stroke subjects with rapid arterial occlusion evaluation scale based suspicion of large vessel occlusion evalu...
Gespeichert in:
| Veröffentlicht in: | International journal of stroke 2019-10, Vol.14 (7), p.734-744 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 744 |
|---|---|
| container_issue | 7 |
| container_start_page | 734 |
| container_title | International journal of stroke |
| container_volume | 14 |
| creator | Abilleira, Sònia Pérez de la Ossa, Natalia Jiménez, Xavier Cardona, Pere Cocho, Dolores Purroy, Francisco Serena, Joaquín Román, Luis San Urra, Xabier Vilaró, Marta Cortés, Jordi González, José Antonio Chamorro, Ángel Gallofré, Miquel Jovin, Tudor Molina, Carlos Cobo, Erik Dávalos, Antoni Ribó, Marc |
| description | Rationale
Optimal pre-hospital delivery pathways for acute stroke patients suspected to harbor a large vessel occlusion have not been assessed in randomized trials.
Aim
To establish whether stroke subjects with rapid arterial occlusion evaluation scale based suspicion of large vessel occlusion evaluated by emergency medical services in the field have higher rates of favorable outcome when transferred directly to an endovascular center (endovascular treatment stroke center), as compared to the standard transfer to the closest local stroke center (local-SC).
Design
Multicenter, superiority, cluster randomized within a cohort trial with blinded endpoint assessment.
Procedure
Eligible patients must be 18 or older, have acute stroke symptoms and not have an immediate life threatening condition requiring emergent medical intervention. They must be suspected to have intracranial large vessel occlusion based on a pre-hospital rapid arterial occlusion evaluation scale of ≥5, be located in geographical areas where the default health authority assigned referral stroke center is a non-thrombectomy capable hospital, and estimated arrival at a thrombectomy capable stroke hospital in less than 7 h from time last seen well. Cluster randomization is performed according to a pre-established temporal sequence (temporal cluster design) with three strata: day/night, distance to the endovascular treatment stroke center, and week/week-end day.
Study outcome
The primary endpoint is the modified Rankin Scale score at 90 days. The primary safety outcome is mortality at 90 days.
Analysis
The primary endpoint based on the modified intention-to-treat population is the distribution of modified Rankin Scale scores at 90 days analyzed under a sequential triangular design. The maximum sample size is 1754 patients, with two planned interim analyses when 701 (40%) and 1227 patients have completed follow-up. Hypothesized common odds ratio is 1.35. |
| doi_str_mv | 10.1177/1747493019852176 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_csuc_</sourceid><recordid>TN_cdi_csuc_recercat_oai_recercat_cat_2072_368057</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1747493019852176</sage_id><sourcerecordid>2232474621</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-6029f500a9c4286ae9c346e54a67930bc314a7033601a43184a0a3a3661eab273</originalsourceid><addsrcrecordid>eNp1UsmOEzEQbSEQs8CdE_JxODR4azvNLWrCIkUaxASurYq7MvHQaWe8DMr8NX-AmyQDQuJg2eWq9175uYriBaOvGdP6DdNSy1pQVk8qzrR6VJyOV6WsZf344SzoSXEWwg2lstJCPS1OBGOSc1afFj8XHoawQk-iI3GNZO4M9OQqevcdSYNDzKk79CEF8s56NJH8jZgNnbuDYFIP_ljtVmRqUsQjyWeINmcC-WHjmlylsM0s2JE5-Gsk3zAE7MmlMX0K1g3EDr_7aCBCDwNZoPc2Or8jF1-mzayZLl69zcyp25Gtd9EZ14-KQEb8KJ-769zG3meFUTDT5ZxbOx9J9Bb6Z8WTFfQBnx_28-Lr-9mi-VjOLz98aqbz0kjOYqkor1cVpVDneKIAayOkwkqC0tnRpRFMgqZCKMpACjaRQEGAUIohLLkW5wXb85qQTJudQ28gtg7sn2BcnGreCjWh1Yi52GPy024ThthubDDYZyPQpdByLnj-ccVZLqUHeu9C8Lhqt95uwO9aRttxONp_hyNDXh7Y03KD3QPgOA25oNwXBLjG9sYlP2SH_k_4C-OsxBU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2232474621</pqid></control><display><type>article</type><title>Transfer to the Local Stroke Center versus Direct Transfer to Endovascular Center of Acute Stroke Patients with Suspected Large Vessel Occlusion in the Catalan Territory (RACECAT): Study protocol of a cluster randomized within a cohort trial</title><source>SAGE Complete A-Z List</source><source>MEDLINE</source><source>Recercat</source><creator>Abilleira, Sònia ; Pérez de la Ossa, Natalia ; Jiménez, Xavier ; Cardona, Pere ; Cocho, Dolores ; Purroy, Francisco ; Serena, Joaquín ; Román, Luis San ; Urra, Xabier ; Vilaró, Marta ; Cortés, Jordi ; González, José Antonio ; Chamorro, Ángel ; Gallofré, Miquel ; Jovin, Tudor ; Molina, Carlos ; Cobo, Erik ; Dávalos, Antoni ; Ribó, Marc</creator><creatorcontrib>Abilleira, Sònia ; Pérez de la Ossa, Natalia ; Jiménez, Xavier ; Cardona, Pere ; Cocho, Dolores ; Purroy, Francisco ; Serena, Joaquín ; Román, Luis San ; Urra, Xabier ; Vilaró, Marta ; Cortés, Jordi ; González, José Antonio ; Chamorro, Ángel ; Gallofré, Miquel ; Jovin, Tudor ; Molina, Carlos ; Cobo, Erik ; Dávalos, Antoni ; Ribó, Marc</creatorcontrib><description>Rationale
Optimal pre-hospital delivery pathways for acute stroke patients suspected to harbor a large vessel occlusion have not been assessed in randomized trials.
Aim
To establish whether stroke subjects with rapid arterial occlusion evaluation scale based suspicion of large vessel occlusion evaluated by emergency medical services in the field have higher rates of favorable outcome when transferred directly to an endovascular center (endovascular treatment stroke center), as compared to the standard transfer to the closest local stroke center (local-SC).
Design
Multicenter, superiority, cluster randomized within a cohort trial with blinded endpoint assessment.
Procedure
Eligible patients must be 18 or older, have acute stroke symptoms and not have an immediate life threatening condition requiring emergent medical intervention. They must be suspected to have intracranial large vessel occlusion based on a pre-hospital rapid arterial occlusion evaluation scale of ≥5, be located in geographical areas where the default health authority assigned referral stroke center is a non-thrombectomy capable hospital, and estimated arrival at a thrombectomy capable stroke hospital in less than 7 h from time last seen well. Cluster randomization is performed according to a pre-established temporal sequence (temporal cluster design) with three strata: day/night, distance to the endovascular treatment stroke center, and week/week-end day.
Study outcome
The primary endpoint is the modified Rankin Scale score at 90 days. The primary safety outcome is mortality at 90 days.
Analysis
The primary endpoint based on the modified intention-to-treat population is the distribution of modified Rankin Scale scores at 90 days analyzed under a sequential triangular design. The maximum sample size is 1754 patients, with two planned interim analyses when 701 (40%) and 1227 patients have completed follow-up. Hypothesized common odds ratio is 1.35.</description><identifier>ISSN: 1747-4930</identifier><identifier>EISSN: 1747-4949</identifier><identifier>DOI: 10.1177/1747493019852176</identifier><identifier>PMID: 31142219</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>92 Biology and other natural sciences ; 92B Mathematical biology in general ; acute stroke ; Biomatemàtica ; Biomathematics ; Classificació AMS ; clinical trial ; drip and ship ; Endovascular Procedures ; Estadística aplicada ; Estadística biosanitària ; Hospital Units ; Humans ; large vessel occlusion ; Matemàtiques i estadística ; mother ship ; Patient Transfer - methods ; pre-hospital ; Research Design ; Stroke - therapy ; Thrombectomy ; Thrombolytic Therapy ; Time-to-Treatment ; transfer models ; Àrees temàtiques de la UPC</subject><ispartof>International journal of stroke, 2019-10, Vol.14 (7), p.734-744</ispartof><rights>2019 World Stroke Organization</rights><rights>info:eu-repo/semantics/openAccess</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-6029f500a9c4286ae9c346e54a67930bc314a7033601a43184a0a3a3661eab273</citedby><cites>FETCH-LOGICAL-c421t-6029f500a9c4286ae9c346e54a67930bc314a7033601a43184a0a3a3661eab273</cites><orcidid>0000-0001-5692-0891 ; 0000-0002-6063-211X ; 0000-0002-1808-5968</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1747493019852176$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1747493019852176$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>230,314,776,780,881,21798,26951,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31142219$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abilleira, Sònia</creatorcontrib><creatorcontrib>Pérez de la Ossa, Natalia</creatorcontrib><creatorcontrib>Jiménez, Xavier</creatorcontrib><creatorcontrib>Cardona, Pere</creatorcontrib><creatorcontrib>Cocho, Dolores</creatorcontrib><creatorcontrib>Purroy, Francisco</creatorcontrib><creatorcontrib>Serena, Joaquín</creatorcontrib><creatorcontrib>Román, Luis San</creatorcontrib><creatorcontrib>Urra, Xabier</creatorcontrib><creatorcontrib>Vilaró, Marta</creatorcontrib><creatorcontrib>Cortés, Jordi</creatorcontrib><creatorcontrib>González, José Antonio</creatorcontrib><creatorcontrib>Chamorro, Ángel</creatorcontrib><creatorcontrib>Gallofré, Miquel</creatorcontrib><creatorcontrib>Jovin, Tudor</creatorcontrib><creatorcontrib>Molina, Carlos</creatorcontrib><creatorcontrib>Cobo, Erik</creatorcontrib><creatorcontrib>Dávalos, Antoni</creatorcontrib><creatorcontrib>Ribó, Marc</creatorcontrib><title>Transfer to the Local Stroke Center versus Direct Transfer to Endovascular Center of Acute Stroke Patients with Suspected Large Vessel Occlusion in the Catalan Territory (RACECAT): Study protocol of a cluster randomized within a cohort trial</title><title>International journal of stroke</title><addtitle>Int J Stroke</addtitle><description>Rationale
Optimal pre-hospital delivery pathways for acute stroke patients suspected to harbor a large vessel occlusion have not been assessed in randomized trials.
Aim
To establish whether stroke subjects with rapid arterial occlusion evaluation scale based suspicion of large vessel occlusion evaluated by emergency medical services in the field have higher rates of favorable outcome when transferred directly to an endovascular center (endovascular treatment stroke center), as compared to the standard transfer to the closest local stroke center (local-SC).
Design
Multicenter, superiority, cluster randomized within a cohort trial with blinded endpoint assessment.
Procedure
Eligible patients must be 18 or older, have acute stroke symptoms and not have an immediate life threatening condition requiring emergent medical intervention. They must be suspected to have intracranial large vessel occlusion based on a pre-hospital rapid arterial occlusion evaluation scale of ≥5, be located in geographical areas where the default health authority assigned referral stroke center is a non-thrombectomy capable hospital, and estimated arrival at a thrombectomy capable stroke hospital in less than 7 h from time last seen well. Cluster randomization is performed according to a pre-established temporal sequence (temporal cluster design) with three strata: day/night, distance to the endovascular treatment stroke center, and week/week-end day.
Study outcome
The primary endpoint is the modified Rankin Scale score at 90 days. The primary safety outcome is mortality at 90 days.
Analysis
The primary endpoint based on the modified intention-to-treat population is the distribution of modified Rankin Scale scores at 90 days analyzed under a sequential triangular design. The maximum sample size is 1754 patients, with two planned interim analyses when 701 (40%) and 1227 patients have completed follow-up. Hypothesized common odds ratio is 1.35.</description><subject>92 Biology and other natural sciences</subject><subject>92B Mathematical biology in general</subject><subject>acute stroke</subject><subject>Biomatemàtica</subject><subject>Biomathematics</subject><subject>Classificació AMS</subject><subject>clinical trial</subject><subject>drip and ship</subject><subject>Endovascular Procedures</subject><subject>Estadística aplicada</subject><subject>Estadística biosanitària</subject><subject>Hospital Units</subject><subject>Humans</subject><subject>large vessel occlusion</subject><subject>Matemàtiques i estadística</subject><subject>mother ship</subject><subject>Patient Transfer - methods</subject><subject>pre-hospital</subject><subject>Research Design</subject><subject>Stroke - therapy</subject><subject>Thrombectomy</subject><subject>Thrombolytic Therapy</subject><subject>Time-to-Treatment</subject><subject>transfer models</subject><subject>Àrees temàtiques de la UPC</subject><issn>1747-4930</issn><issn>1747-4949</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>XX2</sourceid><recordid>eNp1UsmOEzEQbSEQs8CdE_JxODR4azvNLWrCIkUaxASurYq7MvHQaWe8DMr8NX-AmyQDQuJg2eWq9175uYriBaOvGdP6DdNSy1pQVk8qzrR6VJyOV6WsZf344SzoSXEWwg2lstJCPS1OBGOSc1afFj8XHoawQk-iI3GNZO4M9OQqevcdSYNDzKk79CEF8s56NJH8jZgNnbuDYFIP_ljtVmRqUsQjyWeINmcC-WHjmlylsM0s2JE5-Gsk3zAE7MmlMX0K1g3EDr_7aCBCDwNZoPc2Or8jF1-mzayZLl69zcyp25Gtd9EZ14-KQEb8KJ-769zG3meFUTDT5ZxbOx9J9Bb6Z8WTFfQBnx_28-Lr-9mi-VjOLz98aqbz0kjOYqkor1cVpVDneKIAayOkwkqC0tnRpRFMgqZCKMpACjaRQEGAUIohLLkW5wXb85qQTJudQ28gtg7sn2BcnGreCjWh1Yi52GPy024ThthubDDYZyPQpdByLnj-ccVZLqUHeu9C8Lhqt95uwO9aRttxONp_hyNDXh7Y03KD3QPgOA25oNwXBLjG9sYlP2SH_k_4C-OsxBU</recordid><startdate>20191001</startdate><enddate>20191001</enddate><creator>Abilleira, Sònia</creator><creator>Pérez de la Ossa, Natalia</creator><creator>Jiménez, Xavier</creator><creator>Cardona, Pere</creator><creator>Cocho, Dolores</creator><creator>Purroy, Francisco</creator><creator>Serena, Joaquín</creator><creator>Román, Luis San</creator><creator>Urra, Xabier</creator><creator>Vilaró, Marta</creator><creator>Cortés, Jordi</creator><creator>González, José Antonio</creator><creator>Chamorro, Ángel</creator><creator>Gallofré, Miquel</creator><creator>Jovin, Tudor</creator><creator>Molina, Carlos</creator><creator>Cobo, Erik</creator><creator>Dávalos, Antoni</creator><creator>Ribó, Marc</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>XX2</scope><orcidid>https://orcid.org/0000-0001-5692-0891</orcidid><orcidid>https://orcid.org/0000-0002-6063-211X</orcidid><orcidid>https://orcid.org/0000-0002-1808-5968</orcidid></search><sort><creationdate>20191001</creationdate><title>Transfer to the Local Stroke Center versus Direct Transfer to Endovascular Center of Acute Stroke Patients with Suspected Large Vessel Occlusion in the Catalan Territory (RACECAT): Study protocol of a cluster randomized within a cohort trial</title><author>Abilleira, Sònia ; Pérez de la Ossa, Natalia ; Jiménez, Xavier ; Cardona, Pere ; Cocho, Dolores ; Purroy, Francisco ; Serena, Joaquín ; Román, Luis San ; Urra, Xabier ; Vilaró, Marta ; Cortés, Jordi ; González, José Antonio ; Chamorro, Ángel ; Gallofré, Miquel ; Jovin, Tudor ; Molina, Carlos ; Cobo, Erik ; Dávalos, Antoni ; Ribó, Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-6029f500a9c4286ae9c346e54a67930bc314a7033601a43184a0a3a3661eab273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>92 Biology and other natural sciences</topic><topic>92B Mathematical biology in general</topic><topic>acute stroke</topic><topic>Biomatemàtica</topic><topic>Biomathematics</topic><topic>Classificació AMS</topic><topic>clinical trial</topic><topic>drip and ship</topic><topic>Endovascular Procedures</topic><topic>Estadística aplicada</topic><topic>Estadística biosanitària</topic><topic>Hospital Units</topic><topic>Humans</topic><topic>large vessel occlusion</topic><topic>Matemàtiques i estadística</topic><topic>mother ship</topic><topic>Patient Transfer - methods</topic><topic>pre-hospital</topic><topic>Research Design</topic><topic>Stroke - therapy</topic><topic>Thrombectomy</topic><topic>Thrombolytic Therapy</topic><topic>Time-to-Treatment</topic><topic>transfer models</topic><topic>Àrees temàtiques de la UPC</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abilleira, Sònia</creatorcontrib><creatorcontrib>Pérez de la Ossa, Natalia</creatorcontrib><creatorcontrib>Jiménez, Xavier</creatorcontrib><creatorcontrib>Cardona, Pere</creatorcontrib><creatorcontrib>Cocho, Dolores</creatorcontrib><creatorcontrib>Purroy, Francisco</creatorcontrib><creatorcontrib>Serena, Joaquín</creatorcontrib><creatorcontrib>Román, Luis San</creatorcontrib><creatorcontrib>Urra, Xabier</creatorcontrib><creatorcontrib>Vilaró, Marta</creatorcontrib><creatorcontrib>Cortés, Jordi</creatorcontrib><creatorcontrib>González, José Antonio</creatorcontrib><creatorcontrib>Chamorro, Ángel</creatorcontrib><creatorcontrib>Gallofré, Miquel</creatorcontrib><creatorcontrib>Jovin, Tudor</creatorcontrib><creatorcontrib>Molina, Carlos</creatorcontrib><creatorcontrib>Cobo, Erik</creatorcontrib><creatorcontrib>Dávalos, Antoni</creatorcontrib><creatorcontrib>Ribó, Marc</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Recercat</collection><jtitle>International journal of stroke</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abilleira, Sònia</au><au>Pérez de la Ossa, Natalia</au><au>Jiménez, Xavier</au><au>Cardona, Pere</au><au>Cocho, Dolores</au><au>Purroy, Francisco</au><au>Serena, Joaquín</au><au>Román, Luis San</au><au>Urra, Xabier</au><au>Vilaró, Marta</au><au>Cortés, Jordi</au><au>González, José Antonio</au><au>Chamorro, Ángel</au><au>Gallofré, Miquel</au><au>Jovin, Tudor</au><au>Molina, Carlos</au><au>Cobo, Erik</au><au>Dávalos, Antoni</au><au>Ribó, Marc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transfer to the Local Stroke Center versus Direct Transfer to Endovascular Center of Acute Stroke Patients with Suspected Large Vessel Occlusion in the Catalan Territory (RACECAT): Study protocol of a cluster randomized within a cohort trial</atitle><jtitle>International journal of stroke</jtitle><addtitle>Int J Stroke</addtitle><date>2019-10-01</date><risdate>2019</risdate><volume>14</volume><issue>7</issue><spage>734</spage><epage>744</epage><pages>734-744</pages><issn>1747-4930</issn><eissn>1747-4949</eissn><abstract>Rationale
Optimal pre-hospital delivery pathways for acute stroke patients suspected to harbor a large vessel occlusion have not been assessed in randomized trials.
Aim
To establish whether stroke subjects with rapid arterial occlusion evaluation scale based suspicion of large vessel occlusion evaluated by emergency medical services in the field have higher rates of favorable outcome when transferred directly to an endovascular center (endovascular treatment stroke center), as compared to the standard transfer to the closest local stroke center (local-SC).
Design
Multicenter, superiority, cluster randomized within a cohort trial with blinded endpoint assessment.
Procedure
Eligible patients must be 18 or older, have acute stroke symptoms and not have an immediate life threatening condition requiring emergent medical intervention. They must be suspected to have intracranial large vessel occlusion based on a pre-hospital rapid arterial occlusion evaluation scale of ≥5, be located in geographical areas where the default health authority assigned referral stroke center is a non-thrombectomy capable hospital, and estimated arrival at a thrombectomy capable stroke hospital in less than 7 h from time last seen well. Cluster randomization is performed according to a pre-established temporal sequence (temporal cluster design) with three strata: day/night, distance to the endovascular treatment stroke center, and week/week-end day.
Study outcome
The primary endpoint is the modified Rankin Scale score at 90 days. The primary safety outcome is mortality at 90 days.
Analysis
The primary endpoint based on the modified intention-to-treat population is the distribution of modified Rankin Scale scores at 90 days analyzed under a sequential triangular design. The maximum sample size is 1754 patients, with two planned interim analyses when 701 (40%) and 1227 patients have completed follow-up. Hypothesized common odds ratio is 1.35.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>31142219</pmid><doi>10.1177/1747493019852176</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-5692-0891</orcidid><orcidid>https://orcid.org/0000-0002-6063-211X</orcidid><orcidid>https://orcid.org/0000-0002-1808-5968</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1747-4930 |
| ispartof | International journal of stroke, 2019-10, Vol.14 (7), p.734-744 |
| issn | 1747-4930 1747-4949 |
| language | eng |
| recordid | cdi_csuc_recercat_oai_recercat_cat_2072_368057 |
| source | SAGE Complete A-Z List; MEDLINE; Recercat |
| subjects | 92 Biology and other natural sciences 92B Mathematical biology in general acute stroke Biomatemàtica Biomathematics Classificació AMS clinical trial drip and ship Endovascular Procedures Estadística aplicada Estadística biosanitària Hospital Units Humans large vessel occlusion Matemàtiques i estadística mother ship Patient Transfer - methods pre-hospital Research Design Stroke - therapy Thrombectomy Thrombolytic Therapy Time-to-Treatment transfer models Àrees temàtiques de la UPC |
| title | Transfer to the Local Stroke Center versus Direct Transfer to Endovascular Center of Acute Stroke Patients with Suspected Large Vessel Occlusion in the Catalan Territory (RACECAT): Study protocol of a cluster randomized within a cohort trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T11%3A10%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_csuc_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Transfer%20to%20the%20Local%20Stroke%20Center%20versus%20Direct%20Transfer%20to%20Endovascular%20Center%20of%20Acute%20Stroke%20Patients%20with%20Suspected%20Large%20Vessel%20Occlusion%20in%20the%20Catalan%20Territory%20(RACECAT):%20Study%20protocol%20of%20a%20cluster%20randomized%20within%20a%20cohort%20trial&rft.jtitle=International%20journal%20of%20stroke&rft.au=Abilleira,%20S%C3%B2nia&rft.date=2019-10-01&rft.volume=14&rft.issue=7&rft.spage=734&rft.epage=744&rft.pages=734-744&rft.issn=1747-4930&rft.eissn=1747-4949&rft_id=info:doi/10.1177/1747493019852176&rft_dat=%3Cproquest_csuc_%3E2232474621%3C/proquest_csuc_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2232474621&rft_id=info:pmid/31142219&rft_sage_id=10.1177_1747493019852176&rfr_iscdi=true |