A metabolic perspective of late onset Alzheimer’s disease

[Display omitted] After decades of research, the molecular neuropathology of Alzheimer’s disease (AD) is still one of the hot topics in biomedical sciences. Some studies suggest that soluble amyloid β (Aβ) oligomers act as causative agents in the development of AD and could be initiators of its comp...

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Veröffentlicht in:	Pharmacological research 2019-07, Vol.145, p.104255-104255, Article 104255
Hauptverfasser:	Ettcheto, Miren, Cano, Amanda, Busquets, Oriol, Manzine, Patricia Regina, Sánchez-López, Elena, Castro-Torres, Rubén D., Beas-Zarate, Carlos, Verdaguer, Ester, García, María Luisa, Olloquequi, Jordi, Auladell, Carme, Folch, Jaume, Camins, Antoni
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - etiology Alzheimer Disease - metabolism Alzheimer's disease Amyloid beta-Peptides - metabolism Animals c-Jun N-terminal kinase inhibitors Ceramides - metabolism Cognitive Dysfunction - etiology Diabetes Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - metabolism Diabetis Endoplasmic Reticulum Stress Humans Insulin Licochalcone A Malaltia d'Alzheimer Metabolism Metabolisme Neuroinflammation Obesity - complications Reticulum stress Type 2 diabetes mellitus
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