A phase I trial of oncolytic adenovirus ICOVIR-5 administered intravenously to cutaneous and uveal melanoma patients

Oncolytic viruses represent a unique type of agents that combine self-amplification, lytic, and immunostimulatory properties against tumors. A local and locoregional clinical benefit has been demonstrated upon intratumoral injections of an oncolytic herpes virus in melanoma patients, leading to its...

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Veröffentlicht in:	Human gene therapy 2018-09
Hauptverfasser:	García Martin, Margarita, Moreno Olié, Rafael, Gil-Martín, Marta, Cascallò, Manel, Ochoa de Olza, Maria, Cuadra, Carmen, Piulats, Josep M, Navarro-Pérez, Valentin, Domenech, Marta, Alemany Bonastre, Ramon, Salazar Soler, Ramón
Format:	Artikel
Sprache:	eng
Schlagworte:	Herpes Herpesvirus diseases Melanoma Oncogenic viruses Virus oncogènics
Online-Zugang:	Volltext
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