A Dynamic Model of the Proteins that Form the Initial Iron-Sulfur Cluster Biogenesis Machinery in Yeast Mitochondria

The assembly of iron-sulfur clusters (ISCs) in eukaryotes involves the protein Frataxin. Deficits in this protein have been associated with iron inside the mitochondria and impair ISC biogenesis as it is postulated to act as the iron donor for ISCs assembly in this organelle. A pronounced lack of Fr...

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Veröffentlicht in:	Protein Journal 2013-03, Vol.32 (3), p.183-196
Hauptverfasser:	Amela, I., Delicado, P., Gómez, A., Querol, E., Cedano, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	90 Operations research, mathematical programming Animal Anatomy Biochemistry Bioinformatics Bioorganic Chemistry Chemistry Chemistry and Materials Science Classificació AMS Computational Biology Docking Frataxin Friedreich Ataxia - genetics Friedreich Ataxia - metabolism Friedreich's Ataxia Histology Humans Investigació operativa Iron Iron - metabolism Iron compounds Iron-Binding Proteins - chemistry Iron-Binding Proteins - genetics Iron-Binding Proteins - metabolism Iron-sulfur cluster Iron-Sulfur Proteins - chemistry Iron-Sulfur Proteins - genetics Iron-Sulfur Proteins - metabolism Matemàtiques i estadística Mitochondria - chemistry Mitochondria - genetics Mitochondria - metabolism Modeling Models, Biological Models, Molecular Morphology Muscles Organelle Biogenesis Organic Chemistry Protein Conformation Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Sulfur Sulfur - metabolism Sulfur compounds Yeasts Àrees temàtiques de la UPC
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