Quantification of endogenous neurotransmitters and related compounds by liquid chromatography coupled to tandem mass spectrometry

Neurotransmitters are signaling molecules, playing key roles in neuronal communications in the brain. Drug induced changes in neurotransmitters and other brain metabolite concentration may be used to characterize drugs according to their targeted metabolomics profile. Here, we report the development...

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Veröffentlicht in:	Talanta (Oxford) 2019-01, Vol.192, p.93-102
Hauptverfasser:	Olesti, Eulàlia, Rodríguez-Morató, Jose, Gomez-Gomez, Alex, Ramaekers, Johannes G., de la Torre, Rafael, Pozo, Oscar J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain neurotransmitters Cromatografia de líquids Espectrometria de masses Hydrophilic interaction chromatography Liquid chromatography coupled to mass spectrometry Neurotransmissors Psychoactive substances Quantitative method Standard addition
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