Adenosine a(1)-a(2a) Receptor Heteromer As A Possible Target For Early-onset Parkinson's Disease

Parkinson's disease (PD) is a progressive, neurodegenerative disorder that affects ~1% of individuals over the age of 60, which turns to 5% in subjects up to 85 years (de Lau and Breteler, 2006). On the other hand, a form of PD, called early-onset PD (EOPD), arises at an earlier age (

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Hauptverfasser:	Fernández Dueñas, Víctor, Pérez Arevalo, Andrea, Altafaj, Xavier, Ferré, Sergi, Ciruela Alférez, Francisco
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Schlagworte:	Adenosina Adenosine Malaltia de Parkinson Parkinson's disease
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creator	Fernández Dueñas, Víctor Pérez Arevalo, Andrea Altafaj, Xavier Ferré, Sergi Ciruela Alférez, Francisco
description	Parkinson's disease (PD) is a progressive, neurodegenerative disorder that affects ~1% of individuals over the age of 60, which turns to 5% in subjects up to 85 years (de Lau and Breteler, 2006). On the other hand, a form of PD, called early-onset PD (EOPD), arises at an earlier age (
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EOPD patients generally display a slower progression of the disease and present a better response to dopaminergic treatments; however, they may finally develop a full PD symptomatology (i.e., bradykinesia, resting tremor, muscular rigidity and postural instability, drug-induced dyskinesia; Olgiati et al., 2016).</description><language>eng</language><publisher>Frontiers Media</publisher><subject>Adenosina ; Adenosine ; Malaltia de Parkinson ; Parkinson's disease</subject><creationdate>2017-11</creationdate><rights>cc by (c) Fernández Dueñas et al., 2017 info:eu-repo/semantics/openAccess <a href="http://creativecommons.org/licenses/by/3.0/es/">http://creativecommons.org/licenses/by/3.0/es/</a></rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,776,881,26951</link.rule.ids><linktorsrc>$$Uhttps://recercat.cat/handle/2072/332272$$EView_record_in_Consorci_de_Serveis_Universitaris_de_Catalunya_(CSUC)$$FView_record_in_$$GConsorci_de_Serveis_Universitaris_de_Catalunya_(CSUC)$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Fernández Dueñas, Víctor</creatorcontrib><creatorcontrib>Pérez Arevalo, Andrea</creatorcontrib><creatorcontrib>Altafaj, Xavier</creatorcontrib><creatorcontrib>Ferré, Sergi</creatorcontrib><creatorcontrib>Ciruela Alférez, Francisco</creatorcontrib><title>Adenosine a(1)-a(2a) Receptor Heteromer As A Possible Target For Early-onset Parkinson's Disease</title><description>Parkinson's disease (PD) is a progressive, neurodegenerative disorder that affects ~1% of individuals over the age of 60, which turns to 5% in subjects up to 85 years (de Lau and Breteler, 2006). 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title	Adenosine a(1)-a(2a) Receptor Heteromer As A Possible Target For Early-onset Parkinson's Disease
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