Pancreatic Cancer Cell Glycosylation Regulates Cell Adhesion and Invasion through the Modulation of a2b1 Integrin and E-Cadherin Function

In our previous studies we have described that ST3Gal III transfected pancreatic adenocarcinoma Capan-1 and MDAPanc-28 cells show increased membrane expression levels of sialyl-Lewis x (SLex) along with a concomitant decrease in α2,6-sialic acid compared to control cells. Here we have addressed the...

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Veröffentlicht in:PloS one 2014
Hauptverfasser: Bassagañas i Puigdemont, Sònia, Carvalho, Sandra, Dias, Ana M, Pérez Garay, Marta, Ortiz, M.Rosa, Figueras, Joan, Reis, Celso A, Pinho, Salomé S, Peracaula Miró, Rosa
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Sprache:eng
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