The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

A mutation in the HERC2 gene has been linked to a severe neurodevelopmental disorder with similarities to the Angelman syndrome. This gene codifies a protein with ubiquitin ligase activity that regulates the activity of tumor protein p53 and is involved in important cellular processes such as DNA re...

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Veröffentlicht in:	Oncotarget 2016-08
Hauptverfasser:	Cubillos Rojas, Mónica, Schneider, Taiane, Hadjebi, Ouadah, Pedrazza, Leonardo, Rodrigues de Oliveira, Jarbas, Langa, Francina, Guénet, Jean-Louis, Duran i Ferrer, Joan, 1978, Anta i Vinyals, Josep Maria de, Alcántara Horrillo, Soledad, Ruiz, Rocio, Pérez Villegas, Eva María, Aguilar Montilla, Francisco J, Carrión, Ángel M, Armengol, José Ángel, Baple, Emma, Crosby, Andrew H, Bartrons Bach, Ramon, Ventura Pujol, Francesc, Rosa López, José Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavior genetics Creixement fetal Developmental neurobiology Fetal growth Genètica de la conducta Motor ability Motricitat Neurobiologia del desenvolupament Neurones Neurons Proteins Proteïnes Ubiquitin Ubiqüitina
Online-Zugang:	Volltext
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