Targeting the CYP2B1/cyclophosphamide suicide system to fibroblast growth factor receptors result in a potent antitumoral response in pancreatic cancer models

The CYP2B1/cyclophosphamide (CPA) suicide gene therapy approach has been shown to be highly promising in clinical trials for the treatment of pancreatic cancer. However, delivering the therapeutic gene to a sufficient number of tumor cells able to trigger a complete response remains a challenge. Tar...

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Veröffentlicht in:	Human gene therapy 2006-12
Hauptverfasser:	Huch, Meritxell, Abate Daga, Daniel, Roig, Josep Maria, González, Juan Ramón, Fabregat Prous, Joan, Sosnowski Bárbara, Mazo Sánchez, Adela, Fillat i Fonts, Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Càncer Pancreas Pàncrees
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