p-Nitrobenzyloxycarbonyl (pNZ) as Temporary Na-Protecting Group for Mild Solid-Phase Peptide Synthesis. Avoiding Diketopiperazine and Aspartimide Formation

p-Nitrobenzyloxycarbonyl was used as temporary protecting group for the -amino function in solid-phase peptide synthesis. The corresponding derivatives are solids, easy to be synthesized, and perform well in the solid-phase mode. pNZ is removed in practical neutral conditions in the presence of cat...

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Veröffentlicht in:	European journal of organic chemistry 2005
Hauptverfasser:	Isidro Llobet, Albert, Guasch Camell, Judit, Álvarez Domingo, Mercedes, Albericio Palomera, Fernando
Format:	Artikel
Sprache:	eng
Schlagworte:	Combinatorial chemistry Química combinatòria
Online-Zugang:	Volltext
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