Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies

Caveolins are a crucial component of plasma membrane (PM) caveolae but have also been localized to intracellular compartments, including the Golgi complex and lipid bodies. Mutant caveolins associated with human disease show aberrant trafficking to the PM and Golgi accumulation. We now show that the...

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Veröffentlicht in:	Molecular biology of the cell 2005-04, Vol.16 (4), p.2091-2105
Hauptverfasser:	Pol, Albert, Martin, Sally, Fernández, Manuel A, Ingelmo-Torres, Mercedes, Ferguson, Charles, Enrich, Carlos, Parton, Robert G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aparell de Golgi Caveolin 1 Caveolin 3 Caveolins - genetics Caveolins - metabolism Cell Membrane - drug effects Cell Membrane - metabolism Cells, Cultured Cercopithecus aethiops Cholesterol Cholesterol - metabolism Colesterol Cricetinae Fatty acids Fatty Acids - metabolism Golgi apparatus Golgi Apparatus - drug effects Golgi Apparatus - metabolism Membrane proteins Methanol - chemistry Methanol - pharmacology Microscopy, Video Molecular Weight Octoxynol - chemistry Octoxynol - pharmacology Protein Transport Proteïnes de membrana Solubility - drug effects Temperature Time Factors Àcids grassos
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