Molecular Epidemiology and Urothelial Cancer

Tobacco smoking is the main cause of human urothelial cancer. It has been suggested that genetic susceptibility may contribute to the risk, because only a small portion of smokers develops urothelial cancer. Tobacco smoke contains many carcinogens which are activated or detoxified by phase-I or phas...

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Veröffentlicht in:	Journal of UOEH 2007/09/01, Vol.29(3), pp.265-289
Hauptverfasser:	TSUKINO, Hiromasa, OMORI, Hisamatsu, KOHSHI, Kiyotaka, YAMANO, Yuko, KATOH, Takahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Arylamine N-Acetyltransferase - genetics bladder cancer Cytochrome P-450 Enzyme System - genetics cytochrome P450 Genetic Predisposition to Disease - genetics Genotype glutathione S-transferase Glutathione Transferase - genetics Humans Isoenzymes - genetics molecular epidemiology N-acetyltransferase Polymorphism, Genetic Risk Smoking - adverse effects Sulfotransferases - genetics Urologic Neoplasms - epidemiology Urologic Neoplasms - etiology Urothelium
Online-Zugang:	Volltext
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