THE COMPARATIVE β-LACTAMASE RESISTANCE AND INHIBITORY ACTIVITY OF 1-OXA CEPHALOSPORIN, CEFOXITIN AND CEFOTAXIME

The β-lactamase stability and inhibitory activity of 1-oxa cephalosporin, (6R, 7R)-7-[[carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, was investigated and compared to that of cefoxitin and cefota...

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Veröffentlicht in:	Journal of antibiotics 1979, Vol.32(9), pp.909-914
Hauptverfasser:	FU, KWUNG P., NEU, HAROLD C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - drug effects Bacteria - enzymology beta-Lactamase Inhibitors beta-Lactamases - metabolism Cefoxitin - pharmacology Cephalosporinase - metabolism Cephalosporins - pharmacology Drug Interactions Drug Resistance, Microbial
Online-Zugang:	Volltext
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